Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.48 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.47 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | CASP6 | P55212 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19853212 | 0.92 | NAMPT (0.54) | NAMPTMAP4K4CYP17A1MEN1KMT2A | |
| SCHEMBL78108 | 0.92 | MAPT (0.53) | NAMPTMAP4K4CYP17A1TDP1MEN1 | |
| SCHEMBL30464016 | 0.92 | NAMPT (0.43) | NAMPTMAP4K4CYP17A1TDP1MEN1 | |
| Hydrochloric Acid SCHEMBL28891842 | 0.90 | MAPT (0.52) | NAMPTMAP4K4CYP17A1TDP1MEN1 | |
| SCHEMBL3785153 | 0.87 | CYP17A1 (0.59) | NAMPTMAP4K4CYP17A1TDP1MEN1 | |
| SCHEMBL26643063 | 0.87 | PRMT1 (0.49) | NAMPTMAP4K4CYP17A1TDP1MEN1 | |
| SCHEMBL22461364 | 0.86 | POLB (0.67) | NAMPTCYP17A1TDP1MEN1LMNA | |
| SCHEMBL21051137 | 0.86 | NAMPT (0.52) | NAMPTCYP17A1MAPTPSMB8 | |
| Methane SCHEMBL28036476 | 0.86 | CYP17A1 (0.58) | NAMPTMAP4K4CYP17A1TDP1MEN1 | |
| SCHEMBL20865537 | 0.84 | HPGD (0.51) | NAMPTMAP4K4CYP17A1TDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3604287-B1 | PRODUCTION METHOD FOR AMIDATE COMPOUND | KOEI CHEMICAL CO (JP) | 2022-08-03 | — | — | EP | disclosed |
| EP-3495353-B1 | AMIDATE COMPOUND, CATALYST FOR POLYURETHANE PRODUCTION, AND METHOD FOR PRODUCING POLYURETHANE RESIN | KOEI CHEMICAL CO (JP) | 2021-11-17 | — | — | EP | disclosed |
| US-10689478-B2 | Amidate compound, catalyst for polyurethane production, and method for producing polyurethane resin | KOEI CHEMICAL COMPANY, LIMITED (JP) | 2020-06-23 | — | — | US | disclosed |
| EP-3604287-A1 | PRODUCTION METHOD FOR AMIDATE COMPOUND | Koei Chemical Company, Limited (JP) | 2020-02-05 | — | — | EP | disclosed |
| US-20190177464-A1 | AMIDATE COMPOUND, CATALYST FOR POLYURETHANE PRODUCTION, AND METHOD FOR PRODUCING POLYURETHANE RESIN | KOEI CHEMICAL COMPANY, LIMITED (JP) | 2019-06-13 | — | — | US | disclosed |
| EP-3495353-A1 | AMIDATE COMPOUND, CATALYST FOR POLYURETHANE PRODUCTION, AND METHOD FOR PRODUCING POLYURETHANE RESIN | Koei Chemical Company, Limited (JP) | 2019-06-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10689478-B2 | Amidate compound, catalyst for polyurethane production, and method for producing polyurethane resin | ARG1, NIT2, RER1 | NAMPT 1822/4885MAP4K4 4601/4885CYP17A1 1361/4885 |
| US-20190177464-A1 | AMIDATE COMPOUND, CATALYST FOR POLYURETHANE PRODUCTION, AND METHOD FOR PRODUCING POLYURETHANE RESIN | ARG1, NIT2, RER1 | NAMPT 1822/4885MAP4K4 4601/4885CYP17A1 1361/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.