Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28412974 | 1.00 | ALDH1A1 (0.38) | ALDH1A1MAPTHTTNPSR1TP53BP1 | |
| SCHEMBL22467352 | 1.00 | ALDH1A1 (0.38) | ALDH1A1MAPTHTTNPSR1TP53BP1 | |
| SCHEMBL22467357 | 1.00 | ALDH1A1 (0.38) | ALDH1A1MAPTHTTNPSR1TP53BP1 | |
| SCHEMBL28412971 | 1.00 | ALDH1A1 (0.38) | ALDH1A1MAPTHTTNPSR1TP53BP1 | |
| SCHEMBL28412977 | 1.00 | ALDH1A1 (0.38) | ALDH1A1MAPTHTTNPSR1TP53BP1 | |
| SCHEMBL21545089 | 0.87 | SLC6A2 (0.32) | ALDH1A1MAPTHTTNPSR1SLC6A2 | |
| SCHEMBL21455587 | 0.87 | SLC6A2 (0.32) | ALDH1A1MAPTHTTNPSR1SLC6A2 | |
| SCHEMBL21545087 | 0.87 | SLC6A2 (0.32) | ALDH1A1MAPTHTTNPSR1SLC6A2 | |
| SCHEMBL21545088 | 0.87 | SLC6A2 (0.32) | ALDH1A1MAPTHTTNPSR1SLC6A2 | |
| SCHEMBL21545092 | 0.87 | SLC6A2 (0.32) | ALDH1A1MAPTHTTNPSR1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11236055-B2 | Non-systemic TGR5 agonists | Venenum Biodesign, LLC (US) | 2022-02-01 | — | — | US | disclosed |
| US-20200308122-A1 | NOVEL NON-SYSTEMIC TGR5 AGONISTS | Venenum Biodesign, LLC (US) | 2020-10-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200308122-A1 | NOVEL NON-SYSTEMIC TGR5 AGONISTS | GPR119, SSTR5, FFAR3 | ALDH1A1 2874/4885MAPT 4359/4885HTT 4155/4885 |
| US-11236055-B2 | Non-systemic TGR5 agonists | SSTR5, GPR119, FFAR3 | ALDH1A1 2815/4885MAPT 4327/4885HTT 3889/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.