Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 14/20 | 0.51 |
| ▸ | ESR2 | Q92731 | 14/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MIF | P14174 | 1/20 | 0.36 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.33 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21855360 | 0.85 | ESR1 (0.65) | ESR1ESR2CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL21855306 | 0.81 | ESR1 (0.43) | ESR1ESR2MEN1ALDH1A1CYP1A2 | |
| SCHEMBL925617 | 0.75 | ESR1 (0.80) | ESR1ESR2MEN1ALDH1A1CYP1A2 | |
| SCHEMBL22468692 | 0.74 | ADRB3 (0.37) | ESR1ESR2ALDH1A1 | |
| SCHEMBL14498224 | 0.72 | ESR1 (0.74) | ESR1ESR2CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL837133 | 0.72 | HSD17B10 (0.50) | ESR1ESR2MEN1ALDH1A1CYP1A2 | |
| SCHEMBL4649854 | 0.71 | ESR1 (0.67) | ESR1ESR2CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL21855348 | 0.70 | ESR1 (0.51) | ESR1ESR2MIF | |
| SCHEMBL547164 | 0.70 | ESR1 (1.00) | ESR1ESR2MEN1ALDH1A1CYP1A2 | |
| SCHEMBL1171038 | 0.70 | ESR1 (1.00) | ESR1ESR2MEN1ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3946292-A1 | ANDROGEN RECEPTOR MODULATORS AND METHODS FOR USE AS PROTEOLYSIS TARGETING CHIMERA LIGANDS | Essa Pharma, Inc. (CA) | 2022-02-09 | — | — | EP | disclosed |
| WO-2020198711-A1 | ANDROGEN RECEPTOR MODULATORS AND METHODS FOR USE AS PROTEOLYSIS TARGETING CHIMERA LIGANDS | ESSA PHARMA, INC. (CA) | 2020-10-01 | — | — | WO | disclosed |