Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 3/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.47 |
| ▸ | MGLL | Q99685 | 2/20 | 0.47 |
| ▸ | FAAH | O00519 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | NAAA | Q02083 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 4/20 | 0.43 |
| ▸ | CES1 | P23141 | 4/20 | 0.43 |
| ▸ | SQOR | Q9Y6N5 | 2/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.40 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27524906 | 0.98 | PTGS1 (0.50) | PTGS1PTGS2MGLLFAAHL3MBTL1 | |
| SCHEMBL22468785 | 0.98 | PTGS1 (0.50) | PTGS1PTGS2MGLLFAAHL3MBTL1 | |
| SCHEMBL27657704 | 0.98 | PTGS1 (0.50) | PTGS1PTGS2MGLLFAAHL3MBTL1 | |
| SCHEMBL7738969 | 0.98 | PTGS1 (0.50) | PTGS1PTGS2MGLLFAAHL3MBTL1 | |
| SCHEMBL16234075 | 0.94 | MGLL (0.44) | PTGS1PTGS2MGLLFAAHL3MBTL1 | |
| SCHEMBL28163424 | 0.88 | MGLL (0.58) | PTGS1MGLLFAAHPOLBMEN1 | |
| SCHEMBL18485449 | 0.85 | CES1 (0.47) | PTGS1PTGS2MGLLFAAHPOLB | |
| SCHEMBL16244824 | 0.84 | MGLL (0.59) | PTGS1MGLLFAAHL3MBTL1MEN1 | |
| SCHEMBL28760071 | 0.80 | PTGS1 (0.43) | PTGS1PTGS2MGLLFAAHL3MBTL1 | |
| SCHEMBL3794403 | 0.76 | ALDH1A1 (0.47) | PTGS1PTGS2MGLLFAAHPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240209355-A1 | NUCLEIC ACID BINDING PROTEIN FORMULATIONS AND USES THEREOF | SPOTLIGHT THERAPEUTICS | 2024-06-27 | — | — | US | disclosed |
| WO-2022140795-A2 | NUCLEIC ACID BINDING PROTEIN FORMULATIONS AND USES THEREOF | SPOTLIGHT THERAPEUTICS (US) | 2022-06-30 | — | — | WO | disclosed |
| CN-108465112-B | Self-stabilizing linker conjugates | 西雅图基因公司 | 2022-04-29 | — | — | CN | disclosed |
| WO-2022056231-A1 | COMPOSITIONS AND METHODS FOR SCREENING CELL INTERNALIZING AGENTS | SPOTLIGHT THERAPEUTICS (US) | 2022-03-17 | — | — | WO | disclosed |
| CN-114040775-A | Targeted active gene editing agents and methods of use | 光点治疗公司 | 2022-02-11 | — | — | CN | disclosed |
| CN-114026123-A | Targeted active gene editing agents and methods of use | 光点治疗公司 | 2022-02-08 | — | — | CN | disclosed |
| EP-3941515-A1 | TARGETED ACTIVE GENE EDITING AGENT AND METHODS OF USE | Spotlight Therapeutics (US) | 2022-01-26 | — | — | EP | disclosed |
| EP-3941943-A1 | TARGETED ACTIVE GENE EDITING AGENT AND METHODS OF USE | Spotlight Therapeutics (US) | 2022-01-26 | — | — | EP | disclosed |
| US-20220010337-A1 | TARGETED ACTIVE GENE EDITING AGENT AND METHODS OF USE | SPOTLIGHT THERAPEUTICS (US) | 2022-01-13 | — | — | US | disclosed |
| US-20220002695-A1 | TARGETED ACTIVE GENE EDITING AGENT AND METHODS OF USE | SPOTLIGHT THERAPEUTICS (US) | 2022-01-06 | — | — | US | disclosed |
| WO-2021062201-A1 | COMPOSITIONS AND METHODS FOR NUCLEOPROTEIN TARGETING AND EXPRESSION | SPOTLIGHT THERAPEUTICS (US) | 2021-04-01 | — | — | WO | disclosed |
| WO-2020198160-A1 | TARGETED ACTIVE GENE EDITING AGENT AND METHODS OF USE | SPOTLIGHT THERAPEUTICS (US) | 2020-10-01 | — | — | WO | disclosed |
| WO-2020198151-A1 | TARGETED ACTIVE GENE EDITING AGENT AND METHODS OF USE | SPOTLIGHT THERAPEUTICS (US) | 2020-10-01 | — | — | WO | disclosed |