Adipic Acid

Adipic Acid

SCHEMBL224688

CCCCCCCCOC(C)(O)OCCCCCCCC.O=C(O)CCCCC(=O)O

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

SLC18A2SLC6A2SLC6A3

The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 7/20 0.61
PPARG P37231 7/20 0.61
PPARD Q03181 7/20 0.61
PPARA Q07869 7/20 0.61
HDAC11 Q96DB2 5/20 0.61
TSHR P16473 4/20 0.61
PTPN1 P18031 3/20 0.61
ALDH1A1 P00352 3/20 0.61
FABP4 P15090 3/20 0.61
TLR2 O60603 2/20 0.61
TDP1 Q9NUW8 2/20 0.61
KMT2A Q03164 2/20 0.61
ALOX15 P16050 2/20 0.61
HSD17B10 Q99714 2/20 0.61
SLC22A6 Q4U2R8 1/20 0.61
SLC22A8 Q8TCC7 1/20 0.61
MEN1 O00255 1/20 0.61
ESR1 P03372 1/20 0.61
PDE4A P27815 1/20 0.61
PDE3A Q14432 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Adipic Acid SCHEMBL226375 0.93 AKR1B1 (0.56) GPR84PPARGPPARDPPARAHDAC11
SCHEMBL20145201 0.84 CES1 (0.45) TSHRKMT2AMEN1MAPTLMNA
SCHEMBL18377022 0.83 GPR84 (0.57) GPR84PPARGPPARDPPARAHDAC11
Dodecanoate SCHEMBL10577874 0.82 GPR84 (0.81) GPR84PPARGPPARDPPARAHDAC11
Octanoic Acid SCHEMBL28272567 0.81 GPR84 (0.77) GPR84PPARGPPARDPPARAHDAC11
Stearic Acid SCHEMBL8846997 0.81 GPR84 (0.77) GPR84PPARGPPARDPPARAHDAC11
Hexanoate SCHEMBL28788428 0.80 AKR1B1 (0.80) GPR84PPARGPPARDPPARAHDAC11
Dodecanoate SCHEMBL8984827 0.80 GPR84 (0.94) GPR84PPARGPPARDPPARAHDAC11
Octanoic Acid SCHEMBL15093463 0.80 GPR84 (0.94) GPR84PPARGPPARDPPARAHDAC11
SCHEMBL15923147 0.79 GPR84 (0.74) GPR84PPARGPPARDPPARAHDAC11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240093001-A1 RUBBER COMPOSITION FOR HOSE, TRANSMISSION OIL PIPE FOR AUTOMOBILE, AND METHOD FOR PRODUCING SAME THE YOKOHAMA RUBBER CO., LTD. (JP) 2024-03-21 US disclosed
CN-116670218-A Rubber composition for hose, transmission oil pipe for automobile, and method for producing same 横滨橡胶株式会社 2023-08-29 CN disclosed
CN-108623869-B Sealing element 三菱电线工业株式会社 2020-10-20 CN disclosed
EP-2647668-B1 POLYESTER RESIN COMPOSITION AND MOLDED BODY OF SAME ADEKA CORP (JP) 2019-08-14 EP disclosed
EP-3075784-B1 PROCESS FOR PRODUCING MASTERBATCH ADEKA CORP (JP) 2018-10-03 EP disclosed
US-9890256-B2 Process for producing masterbatch ADEKA CORPORATION (JP) 2018-02-13 US disclosed
EP-2796487-B1 METHOD FOR PRODUCING MASTERBATCHES ADEKA CORP (JP) 2017-08-02 EP disclosed
EP-2407514-B1 REINFORCED POLYESTER RESIN COMPOSITION ADEKA CORP (JP) 2017-03-01 EP disclosed
US-9527966-B2 Method for producing masterbatches ADEKA CORPORATION (JP) 2016-12-27 US disclosed
US-20160347917-A1 PROCESS FOR PRODUCING MASTERBATCH ADEKA CORPORATION (JP) 2016-12-01 US disclosed
EP-3075784-A1 PROCESS FOR PRODUCING MASTERBATCH Adeka Corporation (JP) 2016-10-05 EP disclosed
US-20140350139-A1 METHOD FOR PRODUCING MASTERBATCHES ADEKA CORPORATION (JP) 2014-11-27 US disclosed
EP-2796487-A1 METHOD FOR PRODUCING MASTERBATCHES Adeka Corporation (JP) 2014-10-29 EP disclosed
US-8829084-B2 Reinforced polyester resin composition ADEKA CORPORATION (JP) 2014-09-09 US disclosed
EP-2647668-A1 POLYESTER RESIN COMPOSITION AND MOLDED BODY OF SAME Adeka Corporation (JP) 2013-10-09 EP disclosed
US-20130253145-A1 POLYESTER RESIN COMPOSITION AND MOLDED BODY OF SAME ADEKA CORPORATION (JP) 2013-09-26 US disclosed
EP-2407514-A1 REINFORCED POLYESTER RESIN COMPOSITION Adeka Corporation (JP) 2012-01-18 EP disclosed
US-20120004363-A1 REINFORCED POLYESTER RESIN COMPOSITION ADEKA CORPORATION (JP) 2012-01-05 US disclosed