Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPM1D | O15297 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22470143 | 1.00 | PPM1D (0.33) | PPM1D | |
| SCHEMBL22479236 | 0.83 | ALDH1A1 (0.34) | PPM1D | |
| SCHEMBL29290473 | 0.83 | ALDH1A1 (0.34) | PPM1D | |
| SCHEMBL18980144 | 0.78 | PPM1D (0.35) | PPM1D | |
| SCHEMBL22470331 | 0.78 | PPM1D (0.34) | PPM1D | |
| SCHEMBL22470374 | 0.78 | PPM1D (0.34) | PPM1D | |
| SCHEMBL22470329 | 0.78 | PPM1D (0.34) | PPM1D | |
| SCHEMBL2878174 | 0.77 | PPM1D (0.34) | PPM1D | |
| SCHEMBL21954152 | 0.77 | PPM1D (0.34) | PPM1D | |
| SCHEMBL2873724 | 0.77 | PPM1D (0.34) | PPM1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113631228-B | Macrocyclic compounds as STING agonists | 鲁宾有限公司 | 2023-10-13 | — | — | CN | disclosed |
| US-20220144852-A1 | MACROCYCLIC COMPOUNDS AS STING AGONISTS | LUPIN LIMITED (IN) | 2022-05-12 | — | — | US | disclosed |
| EP-3946610-A1 | MACROCYCLIC COMPOUNDS AS STING AGONISTS | Lupin Limited (IN) | 2022-02-09 | — | — | EP | disclosed |
| CN-113631228-A | Macrocyclic compounds as STING agonists | 鲁宾有限公司 | 2021-11-09 | — | — | CN | disclosed |
| WO-2020194160-A1 | MACROCYCLIC COMPOUNDS AS STING AGONISTS | LUPIN LIMITED (IN) | 2020-10-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220144852-A1 | MACROCYCLIC COMPOUNDS AS STING AGONISTS | STING1, CGAS, TBK1 | PPM1D 3915/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.