SCHEMBL22471707

SCHEMBL22471707

C=CC(=O)OC(C)CCCCOP(O)(O)=S

nearest known ligand 0.45

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LPAR3 Q9UBY5 11/20 0.45
LPAR2 Q9HBW0 11/20 0.41
LPAR1 Q92633 5/20 0.39
TSHR P16473 4/20 0.36
ALDH1A1 P00352 1/20 0.36
CYP3A4 P08684 1/20 0.36
HPGD P15428 1/20 0.33
LPAR6 P43657 3/20 0.31
LPAR4 Q99677 3/20 0.31
LPAR5 Q9H1C0 3/20 0.31
FAAH O00519 3/20 0.31
CNR1 P21554 1/20 0.30
CNR2 P34972 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22610051 0.95 LPAR3 (0.42) LPAR3LPAR2LPAR1TSHRALDH1A1
Phosphoric Acid SCHEMBL28328622 0.87 LPAR3 (0.36) LPAR3LPAR2LPAR1TSHRALDH1A1
SCHEMBL5173930 0.87 LPAR3 (0.46) LPAR3LPAR2LPAR1TSHRALDH1A1
SCHEMBL28221577 0.85 LPAR3 (0.49) LPAR3LPAR2LPAR1TSHRALDH1A1
SCHEMBL28298724 0.82 TSHR (0.36) LPAR3LPAR2TSHRALDH1A1CYP3A4
SCHEMBL5174987 0.82 LPAR3 (0.44) LPAR3LPAR2LPAR1TSHRALDH1A1
Ammonia Solution, Strong SCHEMBL28190671 0.81 LPAR3 (0.42) LPAR3LPAR2LPAR1TSHRALDH1A1
SCHEMBL28189957 0.81 LPAR3 (0.42) LPAR3LPAR2LPAR1TSHRALDH1A1
SCHEMBL6557557 0.81 TSHR (0.45) TSHRALDH1A1CYP3A4HPGDFAAH
SCHEMBL19456974 0.81 TSHR (0.45) TSHRALDH1A1CYP3A4HPGDFAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118338879-A Curable composition for dental use 可乐丽则武齿科株式会社 2024-07-12 CN disclosed
US-12011490-B2 Dental photocurable composition excellent in operability and storage stability SHOFU INC. (JP) 2024-06-18 US disclosed
US-20240173211-A1 DENTAL RESIN-REINFORCED GLASS IONOMER CEMENT KIT SHOFU INC. (JP) 2024-05-30 US disclosed
EP-3888616-B1 DENTAL PHOTOCURABLE COMPOSITION EXCELLENT IN COLOR TONE SELECTIVITY SHOFU INC (JP) 2024-05-15 EP disclosed
EP-4321145-A1 DENTAL RESIN-REINFORCED GLASS IONOMER CEMENT KIT Shofu Inc. (JP) 2024-02-14 EP disclosed
CN-112545900-B Dental curable composition containing transition metal adsorbent 株式会社松风 2024-02-13 CN disclosed
CN-113440418-B Dental polymerizable composition 株式会社GC 2023-12-26 CN disclosed
CN-116916872-A Dental composition 可乐丽则武齿科株式会社 2023-10-20 CN disclosed
US-11696874-B2 Dental photocurable composition excellent in color tone selectivity SHOFU INC. (JP) 2023-07-11 US disclosed
CN-111050731-B Non-solvent dental adhesive composition 可乐丽则武齿科株式会社 2023-06-20 CN disclosed
WO-2021049269-A1 GLASS POWDER AND CHEMICAL POLYMERIZATION INITIATOR 株式会社ジーシー 2021-03-18 WO disclosed
WO-2021049268-A1 POLYMERIZABLE DENTAL COMPOSITION 株式会社ジーシー 2021-03-18 WO disclosed
WO-2021049335-A1 DENTAL POLYMERIZABLE COMPOSITION 株式会社ジーシー 2021-03-18 WO disclosed
US-20210000699-A1 POWDER-LIQUID TYPE RESIN-REINFORCED DENTAL GLASS IONOMER CEMENT COMPOSITION SHOFU INC. (JP) 2021-01-07 US disclosed
US-20210000698-A1 TWO-PASTE TYPE DENTAL RESIN-REINFORCED GLASS IONOMER CEMENT COMPOSITION SHOFU INC. (JP) 2021-01-07 US disclosed
EP-3733153-A1 TWO-PASTE TYPE RESIN-REINFORCED DENTAL GLASS IONOMER CEMENT COMPOSITION Shofu Inc. (JP) 2020-11-04 EP disclosed
EP-3733152-A1 POWDER-LIQUID TYPE RESIN-REINFORCED DENTAL GLASS IONOMER CEMENT COMPOSITION Shofu Inc. (JP) 2020-11-04 EP disclosed
WO-2020195026-A1 DENTAL RESTORATIVE MATERIAL SET AND TOOTH RESTORATION METHOD 株式会社ジーシー 2020-10-01 WO disclosed
CN-111050731-A Non-solvent adhesive composition for dental use 可乐丽则武齿科株式会社 2020-04-21 CN disclosed
CN-110785159-A Dual paste type dental curable composition 可乐丽则武齿科株式会社 2020-02-11 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210000698-A1 TWO-PASTE TYPE DENTAL RESIN-REINFORCED GLASS IONOMER CEMENT COMPOSITION ARID2, TAS2R42, MMAB LPAR3 4789/4885LPAR2 4736/4885LPAR1 4807/4885
US-12011490-B2 Dental photocurable composition excellent in operability and storage stability H1-0, CCND1, CCNT1 LPAR3 3842/4885LPAR2 4068/4885LPAR1 3024/4885
US-11696874-B2 Dental photocurable composition excellent in color tone selectivity HBG1, MARK1, KATNA1 LPAR3 4537/4885LPAR2 4496/4885LPAR1 3995/4885
US-20240173211-A1 DENTAL RESIN-REINFORCED GLASS IONOMER CEMENT KIT GRIK1, GRIN2B, GRIK2 LPAR3 4577/4885LPAR2 4592/4885LPAR1 4612/4885
US-20210000699-A1 POWDER-LIQUID TYPE RESIN-REINFORCED DENTAL GLASS IONOMER CEMENT COMPOSITION WDR1, WDR91, WDR5 LPAR3 4705/4885LPAR2 4820/4885LPAR1 4738/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.