SCHEMBL22472467

SCHEMBL22472467

CC1(C)c2ccccc2Oc2c(-c3ccc(-c4cc(-c5ccccc5)cc(-c5ccccc5)c4-c4ccccc4)cc3)cccc21

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DRD1 P21728 1/20 0.36
ADRA2A P08913 2/20 0.31
ADRA2B P18089 2/20 0.31
ADRA2C P18825 1/20 0.31
ALDH1A1 P00352 1/20 0.30
CYP2C9 P11712 1/20 0.30
HPGD P15428 1/20 0.30
ALOX15 P16050 1/20 0.30
ALOX12 P18054 1/20 0.30
BRCA1 P38398 1/20 0.30
HSD17B10 Q99714 1/20 0.30
PDK2 Q15119 1/20 0.30
HPRT1 P00492 1/20 0.30
PTGS1 P23219 1/20 0.30
HTR7 P34969 2/20 0.30
DRD2 P14416 1/20 0.30
HTR1A P08908 1/20 0.30
HTR2B P41595 1/20 0.30
TMEM97 Q5BJF2 1/20 0.30
SIGMAR1 Q99720 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22472518 0.91 DRD1 (0.40) DRD1ADRA2AADRA2BADRA2CALDH1A1
SCHEMBL21130124 0.88 DRD1 (0.44) DRD1ADRA2AADRA2BADRA2CALDH1A1
SCHEMBL25592574 0.86 DRD1 (0.38) DRD1ADRA2AADRA2BADRA2CALDH1A1
SCHEMBL25592570 0.85 DRD1 (0.41) DRD1ALDH1A1CYP2C9HPGDALOX15
SCHEMBL22707960 0.85 DRD1 (0.35) DRD1
SCHEMBL25592572 0.85 DRD1 (0.39) DRD1HTR7HTR1AHTR2BTMEM97
SCHEMBL25592573 0.84 DRD1 (0.42) DRD1ADRA2AADRA2BADRA2CALDH1A1
SCHEMBL15982189 0.83 DRD1 (0.37) DRD1ADRA2AADRA2BADRA2CHTR7
SCHEMBL16787208 0.83 DRD1 (0.37) DRD1ADRA2AADRA2BADRA2CHTR7
SCHEMBL15982205 0.83 DRD1 (0.37) DRD1ADRA2AADRA2BADRA2CHTR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10790455-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2020-09-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10790455-B2 Organic electroluminescent materials and devices ORC3, ALKBH2, ENPP3 DRD1 4324/4885ADRA2A 4076/4885ADRA2B 2218/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.