Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNPAT | O15228 | 1/20 | 0.44 |
| ▸ | KISS1R | Q969F8 | 3/20 | 0.44 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | NPY4R | P50391 | 4/20 | 0.41 |
| ▸ | NPY1R | P25929 | 3/20 | 0.41 |
| ▸ | NPY2R | P49146 | 2/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.41 |
| ▸ | QRFPR | Q96P65 | 1/20 | 0.41 |
| ▸ | FNTA | P49354 | 3/20 | 0.41 |
| ▸ | FNTB | P49356 | 3/20 | 0.41 |
| ▸ | PGGT1B | P53609 | 3/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22139576 | 1.00 | GNPAT (0.44) | GNPATKISS1RPTPN2PTPN1NPY4R | |
| SCHEMBL24453614 | 0.88 | GNPAT (0.45) | GNPATKISS1RPTPN2PTPN1QRFPR | |
| SCHEMBL23106091 | 0.88 | GNPAT (0.47) | GNPATKISS1RNPY4RNPY1RNPY2R | |
| SCHEMBL21503864 | 0.87 | GNPAT (0.46) | GNPATKISS1RNPY4RNPY1RNPY2R | |
| SCHEMBL24064778 | 0.87 | GNPAT (0.46) | GNPATKISS1RNPY4RNPY1RNPY2R | |
| SCHEMBL18823863 | 0.87 | MMP1 (0.48) | GNPATMMP1MMP3ALDH1A1THRB | |
| SCHEMBL20035001 | 0.87 | GNPAT (0.47) | GNPATMMP1MMP3ALDH1A1THRB | |
| SCHEMBL23106087 | 0.84 | GNPAT (0.43) | GNPATKISS1RPTPN2PTPN1QRFPR | |
| SCHEMBL23105991 | 0.84 | KISS1R (0.43) | GNPATKISS1RPTPN2PTPN1NPY4R | |
| SCHEMBL21532937 | 0.81 | NPY4R (0.39) | KISS1RNPY4RNPY1RNPY2RNPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10787480-B2 | Cytotoxic peptides and conjugates thereof | NOVARTIS AG (CH) | 2020-09-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10787480-B2 | Cytotoxic peptides and conjugates thereof | CD47, NGLY1, VIP | GNPAT 3147/4885KISS1R 3017/4885PTPN2 1099/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.