Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 11/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 5/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22472943 | 0.89 | ALDH1A1 (0.38) | ALDH1A1RECQLCHRM1CHRM4CHRM2 | |
| SCHEMBL21597917 | 0.87 | CHRM1 (0.43) | ALDH1A1RECQLCHRM1CHRM4CHRM2 | |
| SCHEMBL22472878 | 0.78 | CHRM4 (0.48) | CHRM1CHRM4CHRM2 | |
| SCHEMBL17001978 | 0.77 | CHRM4 (0.60) | ALDH1A1CHRM1CHRM4CHRM2CHRM5 | |
| SCHEMBL22449313 | 0.76 | CHRM1 (0.40) | ALDH1A1RECQLCHRM1CHRM4CHRM2 | |
| SCHEMBL22472881 | 0.73 | HTR1A (0.45) | ALDH1A1CHRM1CHRM4CHRM2CHRM5 | |
| SCHEMBL12897053 | 0.72 | CHRM1 (0.53) | CHRM1CHRM4CHRM2CHRM5MEN1 | |
| SCHEMBL22472872 | 0.69 | EPHX2 (0.40) | CHRM1CHRM4CHRM2CHRM5CHRM3 | |
| SCHEMBL22472890 | 0.69 | MAPK1 (0.41) | CHRM1CHRM4CHRM2CHRM5CHRM3 | |
| SCHEMBL12897563 | 0.69 | CHRM1 (0.50) | CHRM1CHRM4CHRM2CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10787447-B2 | Pharmaceutical compounds | HEPTARES THERAPEUTICS LIMITED (GB) | 2020-09-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10787447-B2 | Pharmaceutical compounds | CHRM1, CHRM2, CHRM4 | ALDH1A1 2016/4885RECQL 930/4885CHRM1 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.