Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | TARDBP | Q13148 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.50 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12972729 | 0.83 | HSD17B10 (0.55) | HSD17B10KMT2ATARDBPCYP2C9MEN1 | |
| SCHEMBL2633200 | 0.83 | HSD17B10 (0.55) | HSD17B10KMT2ATARDBPCYP2C9MEN1 | |
| SCHEMBL8481372 | 0.79 | LMNA (0.43) | KMT2AALDH1A1LMNATSHR | |
| SCHEMBL21334278 | 0.79 | HSD17B10 (0.50) | HSD17B10KMT2ATARDBPCYP2C9MEN1 | |
| SCHEMBL27413771 | 0.78 | HSD17B10 (0.49) | HSD17B10KMT2ATARDBPCYP2C9MEN1 | |
| SCHEMBL26585895 | 0.76 | HSD17B10 (0.46) | HSD17B10KMT2ATARDBPCYP2C9MEN1 | |
| SCHEMBL20510702 | 0.75 | LMNA (0.40) | KMT2AMEN1ALDH1A1LMNATSHR | |
| SCHEMBL24601927 | 0.74 | HSD17B10 (0.70) | HSD17B10KMT2ATARDBPCYP2C9MEN1 | |
| SCHEMBL8536341 | 0.74 | GAA (0.40) | KMT2AMEN1ALDH1A1LMNATSHR | |
| SCHEMBL1092677 | 0.74 | HSD17B10 (0.70) | HSD17B10KMT2ATARDBPCYP2C9MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10786582-B2 | Gd(III)-dithiolane gold nanoparticle conjugates | NORTHWESTERN UNIVERSITY (US) | 2020-09-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10786582-B2 | Gd(III)-dithiolane gold nanoparticle conjugates | GOLGA3, LGALS3, DSTN | HSD17B10 1935/4885KMT2A 4374/4885TARDBP 1558/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.