Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.57 |
| ▸ | EPHX1 | P07099 | 6/20 | 0.51 |
| ▸ | CASP2 | P42575 | 1/20 | 0.51 |
| ▸ | NAAA | Q02083 | 1/20 | 0.49 |
| ▸ | GLP1R | P43220 | 5/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19249037 | 0.98 | FAAH (0.58) | FAAHEPHX1CASP2NAAAGLP1R | |
| SCHEMBL14981777 | 0.98 | FAAH (0.58) | FAAHEPHX1CASP2NAAAGLP1R | |
| SCHEMBL25665817 | 0.97 | FAAH (0.54) | FAAHEPHX1CASP2NAAAGLP1R | |
| SCHEMBL25588039 | 0.97 | FAAH (0.56) | FAAHEPHX1CASP2NAAAGLP1R | |
| SCHEMBL13296416 | 0.92 | TSHR (0.50) | FAAHEPHX1CASP2GLP1RTSHR | |
| SCHEMBL11846148 | 0.92 | FAAH (0.66) | FAAHEPHX1CASP2NAAAGLP1R | |
| SCHEMBL14685798 | 0.90 | GLP1R (0.47) | FAAHGLP1RTSHRRECQLCNR1 | |
| SCHEMBL23945978 | 0.88 | FAAH (0.57) | FAAHEPHX1CASP2NAAAGLP1R | |
| SCHEMBL23945963 | 0.88 | FAAH (0.57) | FAAHEPHX1CASP2NAAAGLP1R | |
| SCHEMBL30781809 | 0.87 | CASP2 (0.61) | FAAHEPHX1CASP2NAAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10787443-B2 | RAF-degrading conjugate compounds | ZAMBONI CHEM SOLUTIONS INC. (CA) | 2020-09-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10787443-B2 | RAF-degrading conjugate compounds | BRAF, RAF1, ARAF | FAAH 595/4885EPHX1 614/4885CASP2 3004/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.