Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | PRKDC | P78527 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ACE | P12821 | 1/20 | 0.45 |
| ▸ | ECE1 | P42892 | 1/20 | 0.45 |
| ▸ | APAF1 | O14727 | 1/20 | 0.44 |
| ▸ | CDC25B | P30305 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6460809 | 0.69 | ALDH1A1 (0.49) | RXFP1ALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL13721118 | 0.69 | KDM4E (0.51) | ALDH1A1ATML3MBTL1KDM4EELANE | |
| SCHEMBL14559873 | 0.68 | RXFP1 (0.56) | RXFP1ALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL8292259 | 0.68 | RXFP1 (0.55) | RXFP1ALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL18153220 | 0.68 | RXFP1 (0.45) | RXFP1ALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL29987745 | 0.68 | RXFP1 (0.45) | RXFP1ALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL11287130 | 0.67 | PHOSPHO1 (0.50) | ALDH1A1MEN1KMT2AKDM4ECASP3 | |
| SCHEMBL14911731 | 0.67 | PRKDC (0.46) | ALDH1A1PRKDCKDM4EAPAF1CDC25B | |
| SCHEMBL25412172 | 0.65 | MAT2A (0.41) | MEN1KMT2AATML3MBTL1PRKDC | |
| SCHEMBL14280374 | 0.64 | KMT2A (1.00) | ALDH1A1MEN1KMT2AKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110207925-A1 | PROCESS FOR THE PREPARATION OF [1,4,5]-OXADIAZEPINE DERIVATIVES | SYNGENTA CROP PROTECTION, INC. (US) | 2011-08-25 | — | — | US | disclosed |
| EP-1838683-B1 | A PROCESS FOR THE PREPARATION [1,4,5]-OXADIAZEPINE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2009-04-29 | — | — | EP | disclosed |
| EP-1838683-A1 | A PROCESS FOR THE PREPARATION [1,4,5]-OXADIAZEPINE DERIVATIVES | Syngeta Participations AG (CH) | 2007-10-03 | — | — | EP | disclosed |
| WO-2006045587-A1 | A PROCESS FOR THE PREPARATION OF [1,4,5]-OXADIAZEPINE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2006-05-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110207925-A1 | PROCESS FOR THE PREPARATION OF [1,4,5]-OXADIAZEPINE DERIVATIVES | CACNA1D, GRIK4, GRIK5 | RXFP1 2807/4885ALDH1A1 373/4885MEN1 2885/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.