Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.55 |
| ▸ | HINT1 | P49773 | 3/20 | 0.51 |
| ▸ | STING1 | Q86WV6 | 3/20 | 0.50 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.50 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | NT5E | P21589 | 1/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | GSK3A | P49840 | 2/20 | 0.46 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.46 |
| ▸ | TK1 | P04183 | 1/20 | 0.46 |
| ▸ | TGM2 | P21980 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17471689 | 0.92 | ADORA3 (0.59) | ADORA3HINT1STING1PDE3BPDE3A | |
| SCHEMBL3437126 | 0.92 | ADORA3 (0.59) | ADORA3HINT1STING1PDE3BPDE3A | |
| SCHEMBL14946268 | 0.92 | ADORA3 (0.59) | ADORA3HINT1STING1PDE3BPDE3A | |
| SCHEMBL14853765 | 0.92 | ADORA3 (0.59) | ADORA3HINT1STING1PDE3BPDE3A | |
| SCHEMBL3437123 | 0.92 | ADORA3 (0.59) | ADORA3HINT1STING1PDE3BPDE3A | |
| SCHEMBL22644423 | 0.90 | HINT1 (0.55) | ADORA3HINT1STING1PDE3BPDE3A | |
| SCHEMBL15305496 | 0.88 | ADORA3 (0.48) | ADORA3HINT1STING1PDE3BPDE3A | |
| SCHEMBL25581013 | 0.87 | ADORA3 (0.53) | ADORA3HINT1STING1PDE3BPDE3A | |
| SCHEMBL14948887 | 0.85 | ADORA3 (0.56) | ADORA3HINT1STING1PDE3BPDE3A | |
| SCHEMBL562135 | 0.83 | ADORA3 (0.59) | ADORA3HINT1STING1PDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3013340-B9 | SUBSTITUTED NUCLEOSIDES, NUCLEOTIDES AND ANALOGS THEREOF | JANSSEN PHARMACEUTICALS INC (US) | 2023-10-04 | — | — | EP | disclosed |
| EP-3013340-B1 | SUBSTITUTED NUCLEOSIDES, NUCLEOTIDES AND ANALOGS THEREOF | JANSSEN BIOPHARMA INC (US) | 2023-06-07 | — | — | EP | disclosed |
| EP-3160476-B1 | SUBSTITUTED NUCLEOSIDES, NUCLEOTIDES AND ANALOGS THEREOF FOR USE IN THE TREATMENT OF VIRAL INFECTION | JANSSEN BIOPHARMA INC (US) | 2020-09-30 | — | — | EP | disclosed |