Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLG | P54098 | 3/20 | 0.61 |
| ▸ | P2RY2 | P41231 | 9/20 | 0.54 |
| ▸ | P2RY4 | P51582 | 5/20 | 0.51 |
| ▸ | P2RY6 | Q15077 | 5/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26278522 | 1.00 | POLG (0.61) | POLGP2RY2P2RY4P2RY6POLB | |
| SCHEMBL17971851 | 0.90 | POLG (0.51) | POLGP2RY2P2RY4P2RY6POLB | |
| SCHEMBL16575920 | 0.90 | POLG (0.51) | POLGP2RY2P2RY4P2RY6POLB | |
| SCHEMBL6715771 | 0.90 | POLG (0.62) | POLGP2RY2P2RY4P2RY6POLB | |
| SCHEMBL22678641 | 0.90 | POLG (0.62) | POLGP2RY2P2RY4P2RY6POLB | |
| SCHEMBL6715777 | 0.90 | POLG (0.62) | POLGP2RY2P2RY4P2RY6POLB | |
| SCHEMBL16807802 | 0.90 | POLG (0.62) | POLGP2RY2P2RY4P2RY6POLB | |
| SCHEMBL23171226 | 0.89 | POLG (0.60) | POLGP2RY2P2RY4P2RY6POLB | |
| SCHEMBL19590227 | 0.89 | POLG (0.60) | POLGP2RY2P2RY4P2RY6POLB | |
| SCHEMBL17378526 | 0.89 | POLG (0.61) | POLGP2RY2P2RY4P2RY6POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3160476-B1 | SUBSTITUTED NUCLEOSIDES, NUCLEOTIDES AND ANALOGS THEREOF FOR USE IN THE TREATMENT OF VIRAL INFECTION | JANSSEN BIOPHARMA INC (US) | 2020-09-30 | — | — | EP | disclosed |