Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLG | P54098 | 2/20 | 0.62 |
| ▸ | P2RY2 | P41231 | 10/20 | 0.56 |
| ▸ | P2RY4 | P51582 | 5/20 | 0.56 |
| ▸ | P2RY6 | Q15077 | 5/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22678641 | 1.00 | POLG (0.62) | POLGP2RY2P2RY4P2RY6POLB | |
| SCHEMBL6715771 | 1.00 | POLG (0.62) | POLGP2RY2P2RY4P2RY6POLB | |
| SCHEMBL6715777 | 1.00 | POLG (0.62) | POLGP2RY2P2RY4P2RY6POLB | |
| SCHEMBL6258019 | 0.98 | POLG (0.59) | POLGP2RY2P2RY4P2RY6POLB | |
| SCHEMBL22508591 | 0.91 | P2RY2 (0.54) | POLGP2RY2P2RY4P2RY6POLB | |
| SCHEMBL18383663 | 0.91 | P2RY2 (0.53) | POLGP2RY2P2RY4P2RY6POLB | |
| SCHEMBL21896183 | 0.90 | POLB (0.56) | POLGP2RY2P2RY4P2RY6POLB | |
| SCHEMBL21895965 | 0.90 | POLB (0.56) | POLGP2RY2P2RY4P2RY6POLB | |
| SCHEMBL12648719 | 0.90 | POLB (0.56) | POLGP2RY2P2RY4P2RY6POLB | |
| SCHEMBL30237951 | 0.90 | POLB (0.56) | POLGP2RY2P2RY4P2RY6POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015089511-A2 | MODIFIED NUCLEIC ACID MOLECULES AND USES THEREOF | MODERNA THERAPEUTICS, INC. (US) | 2015-06-18 | — | — | WO | disclosed |