SCHEMBL6715771

SCHEMBL6715771

Nc1ccn([C@@H]2O[C@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)C[C@H]2O)c(=O)n1

nearest known ligand 0.62

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ POLG P54098 2/20 0.62
▸ P2RY2 P41231 10/20 0.56
▸ P2RY4 P51582 5/20 0.56
▸ P2RY6 Q15077 5/20 0.56
▸ POLB P06746 1/20 0.55
▸ P2RY12 Q9H244 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16807802 1.00 POLG (0.62) POLGP2RY2P2RY4P2RY6POLB
SCHEMBL22678641 1.00 POLG (0.62) POLGP2RY2P2RY4P2RY6POLB
SCHEMBL6715777 1.00 POLG (0.62) POLGP2RY2P2RY4P2RY6POLB
SCHEMBL6258019 0.98 POLG (0.59) POLGP2RY2P2RY4P2RY6POLB
SCHEMBL22508591 0.91 P2RY2 (0.54) POLGP2RY2P2RY4P2RY6POLB
SCHEMBL18383663 0.91 P2RY2 (0.53) POLGP2RY2P2RY4P2RY6POLB
SCHEMBL21896183 0.90 POLB (0.56) POLGP2RY2P2RY4P2RY6POLB
SCHEMBL21895965 0.90 POLB (0.56) POLGP2RY2P2RY4P2RY6POLB
SCHEMBL12648719 0.90 POLB (0.56) POLGP2RY2P2RY4P2RY6POLB
SCHEMBL30237951 0.90 POLB (0.56) POLGP2RY2P2RY4P2RY6POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240390479-A1 TAIL-CONJUGATED RNAS TIBA BIOTECH (US) 2024-11-28 — — US claimed
WO-2023212213-A1 TAIL-CONJUGATED RNAS TIBA BIOTECH (US) 2023-11-02 — — WO claimed
US-20040248844-A1 Method for the treatment or prevention of Flavivirus infections using nucleoside analogues ISMAILI HICHAM MOULAY ALAOUI (CA) 2004-12-09 — — US claimed
US-6784161-B2 VIRICIDES FOR HEPATITIS C BIOCHEM PHARMA, INC. (CA) 2004-08-31 — — US claimed
US-20020019363-A1 Method for the treatment or prevention of flavivirus infections using nucleoside analogues VIROCHEM PHARMA INC. (CA) 2002-02-14 — — US claimed
US-12636304-B2 — — 2026-05-26 — — US disclosed
US-20260117290-A1 METHOD FOR AMPLIFYING COMPLEMENTARY DNA STRAND IMMUNOGENETEQS, INC. (JP) 2026-04-30 — — US disclosed
US-20260034157-A1 TOOLS TO TARGET NATURAL AND SYNTHETIC NUCLEOTIDE-SENSING PATHWAYS UNIV CALIFORNIA (US) 2026-02-05 — — US disclosed
US-20260028621-A1 METHOD FOR ENCODING DIGITAL DATA ON NUCLEIC ACIDS USING BIOLOGICAL PROCESSES CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2026-01-29 — — US disclosed
EP-4682269-A1 METHOD FOR AMPLIFYING COMPLIMENTARY DNA STRAND Immunogeneteqs, Inc. (JP) 2026-01-21 — — EP disclosed
US-12516302-B2 DNA polymerase theta mutants, methods of producing these mutants, and their uses INSTITUT PASTEUR (FR) 2026-01-06 — — US disclosed
US-20250179572-A1 Photoactive Compounds and Methods for Biomolecule Detection and Sequencing VIBRANT HOLDINGS, LLC 2025-06-05 — — US disclosed
US-6482938-B1 Compounds having energy transfer function and method for DNA base sequencing by using the same WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2002-11-19 — — US disclosed
US-6365350-B1 REACTING RIBONUCLEOTIDE 5'-TRIPHOSPHATES AND 3'-DEOXY NUCLEOTIDE TRIPHOSPHATES WITH RNA POLYMERASE AND DNA FRAGMENT CONTAINING A PROMOTER SEQUENCE FOR THE POLYMERASE, THEN SEPARATING THE TRANSCRIPTION PRODUCT AND SEQUENCING IT THE INSTITUTE OF PHYSICAL AND CHEMICAL RESEARCH (JP) 2002-04-02 — — US disclosed
US-20020019363-A1 Method for the treatment or prevention of flavivirus infections using nucleoside analogues VIROCHEM PHARMA INC. (CA) 2002-02-14 — — US disclosed
WO-2001060315-A2 METHOD FOR THE TREATMENT OR PREVENTION OF FLAVIVIRUS INFECTIONS USING NUCLEOSIDE ANALOGUES SHIRE BIOCHEM INC. (CA) 2001-08-23 — — WO disclosed
US-6265569-B1 HAS ALKYL LINKER INCLUDING DOUBLE OR TRIPLE BOND WHICH ATTACHES FLUORESCENT MOLECULE TO NUCLEOTIDE; FOR TERMINATORS IN DNA SEQUENCING USING RNA POLYMERASES THE INSTITUTE OF PHYSICAL AND CHEMICAL RESEARCH (JP) 2001-07-24 — — US disclosed
EP-1046648-A1 3'-DEOXYRIBONUCLEOTIDE DERIVATIVES THE INSTITUTE OF PHYSICAL & CHEMICAL RESEARCH (JP) 2000-10-25 — — EP disclosed
EP-0978569-A1 METHOD OF DNA SEQUENCING THE INSTITUTE OF PHYSICAL & CHEMICAL RESEARCH (JP) 2000-02-09 — — EP disclosed
EP-0967219-A1 COMPOUNDS HAVING ENERGY TRANSFER FUNCTION AND METHOD FOR DNA BASE SEQUENCING BY USING THE SAME THE INSTITUTE OF PHYSICAL & CHEMICAL RESEARCH (JP) 1999-12-29 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12636304-B2 — RNMT, RNGTT, NSUN2 POLG 1469/4885P2RY2 2861/4885P2RY4 3525/4885
US-20040248844-A1 Method for the treatment or prevention of Flavivirus infections using nucleoside analogues NUDT1, HAVCR2, SLC28A1 POLG 3028/4885P2RY2 1720/4885P2RY4 1225/4885
US-20020019363-A1 Method for the treatment or prevention of flavivirus infections using nucleoside analogues NUDT1, HAVCR2, SLC28A1 POLG 3028/4885P2RY2 1720/4885P2RY4 1225/4885
US-20260028621-A1 METHOD FOR ENCODING DIGITAL DATA ON NUCLEIC ACIDS USING BIOLOGICAL PROCESSES NSUN2, RNMT, RNGTT POLG 543/4885P2RY2 496/4885P2RY4 575/4885
US-20260034157-A1 TOOLS TO TARGET NATURAL AND SYNTHETIC NUCLEOTIDE-SENSING PATHWAYS P2RY2, P2RY1, P2RX1 POLG 893/4885P2RY2 1/4885P2RY4 9/4885
US-20260117290-A1 METHOD FOR AMPLIFYING COMPLEMENTARY DNA STRAND RNGTT, POLRMT, POLM POLG 40/4885P2RY2 4666/4885P2RY4 4758/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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