Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | PRKCA | P17252 | 1/20 | 0.31 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11920353 | 0.93 | AR (0.41) | ARMTNR1AMTNR1BPOLBMAPT | |
| SCHEMBL22475351 | 0.89 | AR (0.39) | ARMTNR1AMTNR1BPOLBMAPT | |
| SCHEMBL22475348 | 0.86 | AR (0.36) | ARMTNR1AMTNR1BPOLBMAPT | |
| SCHEMBL22417598 | 0.86 | AR (0.36) | ARMTNR1AMTNR1BPOLBMAPT | |
| SCHEMBL21162913 | 0.85 | AR (0.36) | ARMTNR1AMTNR1BPOLBMAPT | |
| SCHEMBL11920351 | 0.82 | MTNR1A (0.36) | MTNR1AMTNR1BPOLBTDP1APEX1 | |
| SCHEMBL6880397 | 0.81 | MTNR1A (0.46) | ARMTNR1AMTNR1BPOLBMAPT | |
| SCHEMBL21905015 | 0.80 | CYP3A4 (0.38) | MTNR1AMTNR1BPOLBCYP2D6RECQL | |
| SCHEMBL21163118 | 0.80 | MTNR1A (0.34) | MTNR1AMTNR1BCYP2D6RECQL | |
| SCHEMBL22475346 | 0.79 | NPC1 (0.33) | ARMTNR1AMTNR1BPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2675422-B1 | DENTAL COMPOSITIONS COMPRISING ETHYLENICALLY UNSATURATED ADDITION-FRAGMENTATION AGENT | 3M INNOVATIVE PROPERTIES CO (US) | 2020-09-30 | — | — | EP | disclosed |