Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CASR | P41180 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PRKCA | P17252 | 1/20 | 0.32 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11920353 | 0.96 | AR (0.41) | ARMTNR1AMTNR1BPOLBMAPT | |
| SCHEMBL22475354 | 0.89 | AR (0.38) | ARMTNR1AMTNR1BPOLBMAPT | |
| SCHEMBL22417598 | 0.89 | AR (0.36) | ARMTNR1AMTNR1BPOLBMAPT | |
| SCHEMBL22475348 | 0.89 | AR (0.36) | ARMTNR1AMTNR1BPOLBMAPT | |
| SCHEMBL21162913 | 0.88 | AR (0.36) | ARMTNR1AMTNR1BPOLBMAPT | |
| SCHEMBL21163118 | 0.88 | MTNR1A (0.34) | MTNR1AMTNR1BCYP2D6 | |
| SCHEMBL22417596 | 0.86 | TSHR (0.40) | TSHRPRKCA | |
| SCHEMBL11920351 | 0.83 | MTNR1A (0.36) | MTNR1AMTNR1BPOLB | |
| SCHEMBL21905015 | 0.82 | CYP3A4 (0.38) | MTNR1AMTNR1BPOLBCYP2C9CYP2D6 | |
| SCHEMBL11920352 | 0.81 | TSHR (0.44) | TSHRALDH1A1PRKCATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2675422-B1 | DENTAL COMPOSITIONS COMPRISING ETHYLENICALLY UNSATURATED ADDITION-FRAGMENTATION AGENT | 3M INNOVATIVE PROPERTIES CO (US) | 2020-09-30 | — | — | EP | disclosed |