SCHEMBL2247616

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2241060	0.98	MAPK14 (0.54)	MAPK14BRAFKCNH2KDRABL1
	SCHEMBL2243233	0.93	MAPK14 (0.58)	MAPK14BRAFKCNH2KDRABL1
	SCHEMBL2243353	0.91	MAPK14 (0.58)	MAPK14BRAFKCNH2KDRABL1
	SCHEMBL2243548	0.91	MAPK14 (0.52)	MAPK14BRAFKCNH2RAF1HCK
	SCHEMBL2243541	0.90	MAPK14 (0.51)	MAPK14BRAFKCNH2RAF1HCK
	SCHEMBL2245642	0.89	KCNJ6 (0.60)	MAPK14BRAFKDRRAF1KCNJ6
	SCHEMBL2243890	0.89	MAPK14 (0.51)	MAPK14BRAFKDRABL1FLT1
	SCHEMBL2246430	0.89	KCNJ6 (0.47)	MAPK14BRAFKDRABL1FLT1
	SCHEMBL2242359	0.88	MAPK14 (0.51)	MAPK14BRAFKDRABL1FLT1
	SCHEMBL2243743	0.88	KCNJ6 (0.58)	MAPK14BRAFKDRRAF1KCNJ6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.