Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | DHODH | Q02127 | 3/20 | 0.45 |
| ▸ | DHFR | P00374 | 1/20 | 0.43 |
| ▸ | TNKS | O95271 | 1/20 | 0.43 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.43 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyrimidine SCHEMBL5142222 | 0.92 | PARP1 (0.40) | PARP1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL27761918 | 0.84 | PARP1 (0.43) | PARP1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL27886638 | 0.83 | ALDH1A1 (0.47) | PARP1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL24500765 | 0.83 | DHODH (0.43) | PARP1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL22587488 | 0.82 | ADORA2A (0.46) | MAPTMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL27761915 | 0.82 | PARP1 (0.44) | PARP1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL783767 | 0.79 | PI4KA (0.50) | PARP1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL9172220 | 0.74 | PARP1 (0.49) | PARP1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL17060210 | 0.74 | FGFR1 (0.59) | PARP1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL5383067 | 0.73 | MEN1 (0.50) | PARP1MAPTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109963852-B | Oxoisoquinoline derivatives | 卡尔那生物科学株式会社 | 2021-12-03 | — | — | CN | disclosed |
| US-10793575-B2 | Oxoisoquinoline derivatives | CARNA BIOSCIENCES, INC. (JP) | 2020-10-06 | — | — | US | disclosed |
| CN-109963852-A | Novel oxygen is for isoquinilone derivatives | 卡尔那生物科学株式会社 | 2019-07-02 | — | — | CN | disclosed |
| CN-101438288-A | Regulation of phosphoryl transferase activity of glutamine synthetase | CSIR CORP (ZA) | 2009-05-20 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10793575-B2 | Oxoisoquinoline derivatives | BCL6, BCL6B, BCL3 | PARP1 515/4885MAPT 2780/4885MEN1 810/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.