Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 4/20 | 0.56 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | POLA1 | P09884 | 6/20 | 0.33 |
| ▸ | KARS1 | Q15046 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11704751 | 0.88 | OPRM1 (0.63) | OPRM1OPRK1OPRD1POLA1KDM4E | |
| SCHEMBL21360805 | 0.84 | OPRM1 (0.58) | OPRM1OPRK1OPRD1POLA1GAA | |
| SCHEMBL21360690 | 0.84 | OPRM1 (0.65) | OPRM1OPRK1OPRD1KARS1NR1I2 | |
| SCHEMBL21360722 | 0.84 | OPRM1 (0.58) | OPRM1OPRK1OPRD1POLA1GAA | |
| SCHEMBL21360678 | 0.84 | OPRM1 (0.65) | OPRM1OPRK1OPRD1KARS1NR1I2 | |
| SCHEMBL21360866 | 0.81 | OPRM1 (0.55) | OPRM1OPRK1OPRD1POLA1KDM4E | |
| SCHEMBL21360689 | 0.80 | OPRM1 (0.50) | OPRM1OPRK1POLA1MEN1KMT2A | |
| SCHEMBL21042348 | 0.77 | OPRM1 (0.69) | OPRM1OPRK1POLA1ALDH1A1MEN1 | |
| SCHEMBL21424563 | 0.77 | OPRM1 (0.69) | OPRM1OPRK1POLA1ALDH1A1MEN1 | |
| SCHEMBL21424663 | 0.77 | OPRM1 (0.69) | OPRM1OPRK1POLA1ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3401306-B1 | DEZOCINE ANALOGUE | SHANDONG DANHONG PHARMACEUTICAL CO LTD (CN) | 2020-09-30 | — | — | EP | disclosed |