Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 4/20 | 0.55 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 2/20 | 0.35 |
| ▸ | POLA1 | P09884 | 6/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.31 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11704751 | 0.87 | OPRM1 (0.63) | OPRM1GAAALOX12HTTSMN1; SMN2 | |
| SCHEMBL21360785 | 0.84 | OPRM1 (0.63) | OPRM1POLA1OPRD1OPRK1 | |
| SCHEMBL21360822 | 0.84 | OPRM1 (0.63) | OPRM1POLA1OPRD1OPRK1 | |
| SCHEMBL21360722 | 0.83 | OPRM1 (0.58) | OPRM1GAAHTTPOLA1OPRD1 | |
| SCHEMBL21360805 | 0.83 | OPRM1 (0.58) | OPRM1HTR2AGAAPOLA1OPRD1 | |
| SCHEMBL22477265 | 0.81 | OPRM1 (0.56) | OPRM1GAAPOLA1OPRD1OPRK1 | |
| SCHEMBL21042348 | 0.76 | OPRM1 (0.69) | OPRM1HTR2APOLA1OPRK1ALDH1A1 | |
| SCHEMBL21424663 | 0.76 | OPRM1 (0.69) | OPRM1HTR2APOLA1OPRK1ALDH1A1 | |
| SCHEMBL21424563 | 0.76 | OPRM1 (0.69) | OPRM1HTR2APOLA1OPRK1ALDH1A1 | |
| SCHEMBL11700412 | 0.76 | OPRM1 (0.69) | OPRM1HTR2APOLA1OPRK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10414718-B2 | Dezocine analogue | SHANDONG DANHONG PHARMACEUTICAL CO., LTD. (CN) | 2019-09-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10414718-B2 | Dezocine analogue | DDO, DDC, DAO | OPRM1 9/4885HTR2A 110/4885GAA 1688/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.