Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 7/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | ABL1 | P00519 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | SCD | O00767 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21394864 | 0.85 | LMNA (0.62) | LMNARAB9AMAPTKMT2ANPC1 | |
| SCHEMBL22479584 | 0.81 | MEN1 (0.48) | LMNARAB9AMAPTKMT2ANPC1 | |
| SCHEMBL21394885 | 0.80 | SCD (0.56) | LMNARAB9AMAPTKMT2ANPC1 | |
| SCHEMBL29353929 | 0.80 | RAB9A (0.43) | LMNARAB9AMAPTKMT2ANPC1 | |
| SCHEMBL21394436 | 0.80 | RAB9A (0.43) | LMNARAB9AMAPTKMT2ANPC1 | |
| SCHEMBL21395177 | 0.79 | MEN1 (0.56) | LMNARAB9AMAPTKMT2ANPC1 | |
| SCHEMBL21394796 | 0.78 | POLB (0.59) | LMNARAB9AMAPTKMT2ANPC1 | |
| SCHEMBL29356996 | 0.78 | POLB (0.59) | LMNARAB9AMAPTKMT2ANPC1 | |
| SCHEMBL21394669 | 0.77 | RAB9A (0.56) | LMNARAB9AMAPTKMT2ANPC1 | |
| SCHEMBL21394799 | 0.77 | LMNA (0.45) | LMNARAB9AMAPTKMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020198026-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |