Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | PLAU | P00749 | 2/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | F12 | P00748 | 1/20 | 0.41 |
| ▸ | NCF1 | P14598 | 1/20 | 0.41 |
| ▸ | NOS3 | P29474 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL467327 | 0.75 | MAPT (0.43) | KDM4EMAPTNPC1RAB9AL3MBTL1 | |
| SCHEMBL199273 | 0.74 | PLAU (0.60) | KDM4EMAPTNPC1RAB9AL3MBTL1 | |
| SCHEMBL29923403 | 0.74 | PLAU (0.60) | KDM4EMAPTNPC1RAB9AL3MBTL1 | |
| SCHEMBL30522769 | 0.72 | PLAU (0.58) | KDM4EMAPTNPC1RAB9AL3MBTL1 | |
| SCHEMBL12223316 | 0.70 | PLAU (0.56) | KDM4EMAPTNPC1RAB9AL3MBTL1 | |
| SCHEMBL13978866 | 0.70 | PLAU (0.56) | KDM4EMAPTNPC1RAB9AL3MBTL1 | |
| SCHEMBL158912 | 0.70 | BCHE (0.58) | KDM4EMAPTNPC1RAB9AL3MBTL1 | |
| SCHEMBL29986041 | 0.70 | BCHE (0.58) | KDM4EMAPTNPC1RAB9AL3MBTL1 | |
| SCHEMBL12112873 | 0.69 | MAPT (0.58) | KDM4EMAPTNPC1RAB9AL3MBTL1 | |
| SCHEMBL21810846 | 0.69 | MAPT (0.43) | KDM4EMAPTNPC1RAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105308026-A | Cyclic azine compound having adamantyl group, production method, and organic electroluminescent element containing said compound as constituent | TOSOH CORP | 2016-02-03 | — | — | CN | disclosed |
| EP-2341775-A1 | INHIBITORS OF JANUS KINASES | Merck & Co., Inc. (US) | 2011-07-13 | — | — | EP | disclosed |
| WO-2010014453-A1 | INHIBITORS OF JANUS KINASES | MERCK & CO., INC. (US) | 2010-02-04 | — | — | WO | disclosed |
| EP-1037868-B1 | $g(a)-HYDROXY, -AMINO, AND HALO DERIVATIVES OF $g(b)-SULFONYL HYDROXAMIC ACIDS AS MATRIX METALLOPROTEINASES INHIBITORS | UPJOHN CO (US) | 2003-02-05 | — | — | EP | disclosed |