SCHEMBL224824

SCHEMBL224824

Nc1cc2ccccc2cc1SSc1cc2ccccc2cc1N

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.50
KMT2A Q03164 3/20 0.50
APOBEC3G Q9HC16 2/20 0.50
MAPT P10636 2/20 0.50
NPSR1 Q6W5P4 1/20 0.50
IDO1 P14902 1/20 0.43
ALDH1A1 P00352 5/20 0.42
HSD17B10 Q99714 5/20 0.42
CYP3A4 P08684 4/20 0.42
NPC1 O15118 3/20 0.42
RAB9A P51151 1/20 0.42
CASP1 P29466 3/20 0.41
CASP7 P55210 3/20 0.41
ALOX15 P16050 3/20 0.41
HBB P68871 2/20 0.41
HIF1A Q16665 2/20 0.41
TDP1 Q9NUW8 1/20 0.41
PDPK1 O15530 1/20 0.38
HPGD P15428 3/20 0.38
SMN1; SMN2 Q16637 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13892881 0.81 IDO1 (0.41) MEN1KMT2AAPOBEC3GMAPTNPSR1
SCHEMBL139321 0.78 CYP3A4 (0.55) MEN1KMT2AMAPTIDO1ALDH1A1
SCHEMBL29391862 0.78 CYP3A4 (0.55) MEN1KMT2AMAPTIDO1ALDH1A1
SCHEMBL23783712 0.76 LMNA (0.49) KMT2AMAPTNPSR1ALDH1A1HSD17B10
SCHEMBL20267099 0.75 ALDH1A1 (0.52) MEN1KMT2AMAPTIDO1ALDH1A1
Ammonia Solution, Strong SCHEMBL6034560 0.75 ALDH1A1 (0.52) MEN1KMT2AMAPTIDO1ALDH1A1
SCHEMBL15939956 0.73 ALDH1A1 (0.62) MEN1KMT2AMAPTIDO1ALDH1A1
SCHEMBL20735484 0.73 ALDH1A1 (0.62) MEN1KMT2AMAPTIDO1ALDH1A1
SCHEMBL30692312 0.73 ALDH1A1 (0.62) MEN1KMT2AMAPTIDO1ALDH1A1
SCHEMBL29553137 0.73 ALDH1A1 (0.62) MEN1KMT2AMAPTIDO1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 561 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6998444-B2 Vulcanization accelerator in crosslinked cis-polybutadiene core for increase compression and low coefficient of restitution, without causing any isomerism; use small amounts of crosslinker zinc diacrylate ACUSHNET COMPANY (US) 2006-02-14 US claimed
US-20050256274-A1 Golf ball core compositions JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2005-11-17 US claimed
US-6960629-B2 Use of a metallic mercaptothiazole or metallic mercaptobenzothiazole in golf ball compositions ACUSHNET COMPANY (US) 2005-11-01 US claimed
US-20040230006-A1 Use of a metallic mercaptothiazole or metallic mercaptobenzothiazole in golf ball compositions JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2004-11-18 US claimed
US-20040230005-A1 Use of a metallic mercaptothiazole or metallic mercaptobenzothiazole in golf ball compositions ACUSHNET COMPANY 2004-11-18 US claimed
US-10933285-B2 Multi-layer core golf ball ACUSHNET COMPANY (US) 2021-03-02 US disclosed
US-20200197757-A1 MULTI-LAYER CORE GOLF BALL ACUSHNET COMPANY (US) 2020-06-25 US disclosed
US-10596419-B2 Multi-layer core golf ball ACUSHNET COMPANY (US) 2020-03-24 US disclosed
US-20200086174-A1 A GOLF BALL COMPRISING A VERY-LOW MELT FLOW INNER COVER LAYER COMPOSITION JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2020-03-19 US disclosed
US-20200047033-A1 MULTI-LAYER CORE GOLF BALL ACUSHNET COMPANY (US) 2020-02-13 US disclosed
US-10478674-B2 Golf ball comprising a very-low melt flow inner cover layer composition ACUSHNET COMPANY (US) 2019-11-19 US disclosed
US-10478675-B2 Multi-layer core golf ball ACUSHNET COMPANY (US) 2019-11-19 US disclosed
US-20020006837-A1 Wound golf ball having cast polyurethane cover ACUSHNET COMPANY 2002-01-17 US disclosed
WO-2000038794-A9 LOW COMPRESSION, RESILIENT GOLF BALLS INCLUDING AN ORGANOSULFUR CATALYST AND METHOD FOR MAKING SAME ACUSHNET CO (US) 2001-11-01 WO disclosed
US-20010024982-A1 Thin-layer-covered multilayer golf ball JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2001-09-27 US disclosed
US-6291592-B1 HARDNESS, STIFFNESS ACUSHNET COMPANY 2001-09-18 US disclosed
WO-2000038794-A1 LOW COMPRESSION, RESILIENT GOLF BALLS INCLUDING AN ORGANOSULFUR CATALYST AND METHOD FOR MAKING SAME ACUSHNET COMPANY (US) 2000-07-06 WO disclosed
WO-2000038793-A1 LOW COMPRESSION, RESILIENT GOLF BALLS INCLUDING ELEMENTAL CATALYST AND METHOD FOR MAKING SAME ACUSHNET COMPANY (US) 2000-07-06 WO disclosed
WO-2000038795-A1 LOW COMPRESSION, RESILIENT GOLF BALLS INCLUDING AROMATIC CATALYST AND METHOD FOR MAKING SAME ACUSHNET COMPANY (US) 2000-07-06 WO disclosed
US-5816939-A AGING RESISTANCE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 1998-10-06 US disclosed