Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 20/20 | 0.83 |
| ▸ | SCN5A | Q14524 | 13/20 | 0.61 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | SCN4A | P35499 | 1/20 | 0.49 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pf-05241328 SCHEMBL30275387 | 0.91 | SCN9A (1.00) | SCN9ASCN5ACYP2C8CYP2C9CYP2B6 | |
| Pf-05241328 SCHEMBL10324699 | 0.91 | SCN9A (1.00) | SCN9ASCN5ACYP2C8CYP2C9CYP2B6 | |
| SCHEMBL10380265 | 0.88 | SCN9A (0.82) | SCN9ASCN5ACYP2C8CYP2C9CYP2B6 | |
| SCHEMBL10380147 | 0.87 | SCN9A (0.81) | SCN9ASCN5ACYP2C8CYP2C9CYP2B6 | |
| SCHEMBL22483957 | 0.86 | SCN9A (0.84) | SCN9ASCN5A | |
| SCHEMBL22484230 | 0.86 | SCN9A (0.62) | SCN9ASCN5ACYP2C9 | |
| SCHEMBL22484228 | 0.86 | SCN9A (0.62) | SCN9ASCN5A | |
| SCHEMBL10324973 | 0.84 | SCN9A (0.76) | SCN9ASCN5ACYP2C8CYP2C9CYP2B6 | |
| SCHEMBL10378866 | 0.82 | SCN9A (0.83) | SCN9ASCN5ACYP2C8CYP2C9CYP2B6 | |
| SCHEMBL10379156 | 0.82 | SCN9A (0.83) | SCN9ASCN5ACYP2C8CYP2C9CYP2B6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020192588-A1 | ALKYLSULFAMOYL INDAZOLE CARBOXAMIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL USE THEREOF | 上海海雁医药科技有限公司 | 2020-10-01 | — | — | WO | disclosed |