Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | GSK3B | P49841 | 1/20 | 0.49 |
| ▸ | DAO | P14920 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | LOX | P28300 | 1/20 | 0.34 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13614249 | 0.82 | DAO (0.66) | CA2GSK3BDAOTP53RAB9A | |
| SCHEMBL25363505 | 0.82 | DAO (0.46) | GSK3BDAOTP53RAB9AUSP2 | |
| SCHEMBL10447678 | 0.82 | DAO (0.50) | CA2GSK3BDAOTP53RAB9A | |
| SCHEMBL11636124 | 0.80 | GSK3B (0.49) | CA2GSK3BDAOTP53RAB9A | |
| Hydrochloric Acid SCHEMBL25366949 | 0.80 | DAO (0.44) | GSK3BDAOTP53RAB9AUSP2 | |
| SCHEMBL12407032 | 0.79 | LOXL2 (0.49) | CA2DAOTP53RAB9AUSP2 | |
| SCHEMBL4475685 | 0.79 | RAB9A (0.45) | DAOTP53RAB9AUSP2MAPT | |
| SCHEMBL1706391 | 0.78 | DAO (0.52) | CA2GSK3BDAOTP53RAB9A | |
| SCHEMBL25364110 | 0.77 | DAO (0.39) | CA2GSK3BDAOTP53RAB9A | |
| SCHEMBL25364217 | 0.77 | MAPT (0.43) | DAORAB9AMAPTGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020198062-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ACHILLION PHARMACEUTICALS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |