SCHEMBL22487560

SCHEMBL22487560

c1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(-n4c5ccccc5c5c6c(ccc54)oc4ccccc46)c4c3sc3ccccc34)n2)cc1

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.31
HPGD P15428 1/20 0.31
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22487566 0.93
SCHEMBL22486627 0.89
SCHEMBL22487671 0.89 TSHR (0.33) ALDH1A1HPGDTSHR
SCHEMBL22487662 0.89 ALDH1A1 (0.31) ALDH1A1HPGDTSHR
SCHEMBL22486565 0.87
SCHEMBL22486596 0.87 KDM4E (0.35)
SCHEMBL27021021 0.86 ACP1 (0.32) ALDH1A1HPGDTSHR
SCHEMBL22486594 0.85 ALOX5 (0.31)
SCHEMBL22487582 0.85
SCHEMBL22485969 0.85 MAPT (0.36) ALDH1A1HPGDTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020197253-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DIODE COMPRISING SAME 주식회사 엘지화학 2020-10-01 WO disclosed