Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.38 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.37 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22487790 | 0.96 | ADORA1 (0.38) | HRH4ADORA1ADORA3ADORA2ASMPD3 | |
| SCHEMBL22858756 | 0.84 | HRH4 (0.36) | HRH4SMPD3GAAHTTPOLB | |
| SCHEMBL8957952 | 0.81 | ALDH1A1 (0.41) | HRH4MEN1KMT2A | |
| SCHEMBL13318361 | 0.79 | HRH4 (0.35) | HRH4SMPD3 | |
| Hydrochloric Acid SCHEMBL14716148 | 0.78 | HDAC6 (0.36) | HRH4SMPD3HTT | |
| Hydrochloric Acid SCHEMBL28836282 | 0.78 | HRH4 (0.34) | HRH4SMPD3 | |
| SCHEMBL12989184 | 0.77 | HRH4 (0.38) | HRH4ADORA1ADORA3ADORA2ADDAH1 | |
| SCHEMBL23642016 | 0.75 | PDCD1 (0.40) | ADORA1ADORA3ADORA2ADDAH1 | |
| SCHEMBL7711700 | 0.75 | HRH4 (0.33) | HRH4SMPD3 | |
| SCHEMBL19152671 | 0.73 | SRC (0.33) | ADORA1ADORA3ADORA2ADDAH1TNKS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230000993-A1 | SILICON BASED DRUG CONJUGATES AND METHODS OF USING SAME | BLINKBIO INC (US) | 2023-01-05 | — | — | US | disclosed |
| EP-3081569-B1 | IMIDAZOLE DERIVATIVE USED AS ANTIVIRAL AGENT AND USE THEREOF IN PREPARATION OF MEDICAMENT | SHANDONG DANHONG PHARMACEUTICAL CO LTD (CN) | 2019-09-18 | — | — | EP | disclosed |
| WO-2019055540-A1 | COMPOUNDS AS RAS INHIBITORS AND USE THEREOF | D.E. SHAW RESEARCH, LLC (US) | 2019-03-21 | — | — | WO | disclosed |
| US-20070043045-A1 | Novel high affinity thiophene-based and furan-based kinase ligands | SCHERING CORPORATION | 2007-02-22 | — | — | US | disclosed |
| US-5478539-A | Solvent extraction by complexing the metal oxyanion with a benzimidazole | ZENECA LIMITED (GB) | 1995-12-26 | — | — | US | disclosed |
| US-5213777-A | Extraction of uranium values using an imidazole extractant | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230000993-A1 | SILICON BASED DRUG CONJUGATES AND METHODS OF USING SAME | CD44, MSN, AS3MT | HRH4 3015/4885ADORA1 4484/4885ADORA3 4145/4885 |
| US-20070043045-A1 | Novel high affinity thiophene-based and furan-based kinase ligands | CDKL2, CDK2, CDKL1 | HRH4 2993/4885ADORA1 4237/4885ADORA3 4176/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.