Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKACA | P17612 | 4/20 | 0.42 |
| ▸ | PRKCD | Q05655 | 4/20 | 0.42 |
| ▸ | PRKD3 | O94806 | 3/20 | 0.42 |
| ▸ | PRKACG | P22612 | 3/20 | 0.42 |
| ▸ | PRKACB | P22694 | 3/20 | 0.42 |
| ▸ | PRKCZ | Q05513 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | PRKCG | P05129 | 2/20 | 0.42 |
| ▸ | PRKCB | P05771 | 2/20 | 0.42 |
| ▸ | PRKCA | P17252 | 2/20 | 0.42 |
| ▸ | PRKCH | P24723 | 2/20 | 0.42 |
| ▸ | PRKCI | P41743 | 2/20 | 0.42 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.42 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.42 |
| ▸ | PRKD1 | Q15139 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22489772 | 0.92 | PRKACA (0.40) | PRKACAPRKCDPRKD3PRKACGPRKACB | |
| SCHEMBL22467207 | 0.90 | PRKACA (0.46) | PRKACAPRKCDPRKD3PRKACGPRKACB | |
| SCHEMBL22467344 | 0.87 | HCRTR1 (0.46) | KMT2ASMN1; SMN2MEN1CYP3A4CYP2D6 | |
| SCHEMBL22467385 | 0.86 | ALDH1A1 (0.49) | KMT2ASMN1; SMN2MEN1CYP3A4TSHR | |
| SCHEMBL22467442 | 0.85 | PRKACA (0.44) | PRKACAPRKCDPRKD3PRKACGPRKACB | |
| SCHEMBL22467419 | 0.85 | PRKACA (0.44) | PRKACAPRKCDPRKD3PRKACGPRKACB | |
| Hydrochloric Acid SCHEMBL22467498 | 0.84 | PRKACA (0.44) | PRKACAPRKCDPRKD3PRKACGPRKACB | |
| SCHEMBL22467398 | 0.83 | KMT2A (0.43) | KMT2ASMN1; SMN2MEN1CYP3A4RAB9A | |
| SCHEMBL22489892 | 0.83 | KMT2A (0.43) | KMT2ASMN1; SMN2MEN1CYP3A4RAB9A | |
| SCHEMBL22467401 | 0.83 | KMT2A (0.43) | KMT2ASMN1; SMN2MEN1CYP3A4RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11236055-B2 | Non-systemic TGR5 agonists | Venenum Biodesign, LLC (US) | 2022-02-01 | — | — | US | disclosed |
| US-20200308122-A1 | NOVEL NON-SYSTEMIC TGR5 AGONISTS | Venenum Biodesign, LLC (US) | 2020-10-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200308122-A1 | NOVEL NON-SYSTEMIC TGR5 AGONISTS | GPR119, SSTR5, FFAR3 | PRKACA 1900/4885PRKCD 2077/4885PRKD3 2337/4885 |
| US-11236055-B2 | Non-systemic TGR5 agonists | SSTR5, GPR119, FFAR3 | PRKACA 1890/4885PRKCD 2395/4885PRKD3 2501/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.