SCHEMBL22490116

SCHEMBL22490116

Cc1ccc(-c2c(F)c(F)c(-c3cccs3)c3nsnc23)s1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DHODH Q02127 1/20 0.35
ALDH1A1 P00352 6/20 0.33
CYP1A2 P05177 2/20 0.33
KDM4E B2RXH2 5/20 0.33
GAA P10253 3/20 0.33
MEN1 O00255 3/20 0.33
KMT2A Q03164 3/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
NPC1 O15118 2/20 0.33
RAB9A P51151 1/20 0.33
ACHE P22303 1/20 0.33
MAPT P10636 3/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
LMNA P02545 1/20 0.33
GLA P06280 1/20 0.33
HPGD P15428 2/20 0.32
NPSR1 Q6W5P4 1/20 0.32
MGAM O43451 1/20 0.32
SI P14410 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16185945 0.89 DPP4 (0.39) DHODHALDH1A1CYP1A2KDM4EGAA
SCHEMBL726615 0.87 DHODH (0.41) DHODHALDH1A1CYP1A2KDM4EMEN1
SCHEMBL15249165 0.87 ALDH1A1 (0.35) ALDH1A1KDM4EMEN1KMT2ANPC1
SCHEMBL16185944 0.84 DHODH (0.34) DHODHALDH1A1CYP1A2KDM4EGAA
SCHEMBL1814915 0.80 HSD17B10 (0.38) DHODHALDH1A1CYP1A2KDM4EGAA
SCHEMBL25450958 0.80 NPC1 (0.33) ALDH1A1NPC1MAPTHSD17B10GFER
SCHEMBL18665861 0.79 RAB9A (0.36) DHODHALDH1A1CYP1A2KDM4EGAA
SCHEMBL23038590 0.78 GRIN2D (0.37) DHODHALDH1A1CYP1A2KDM4EGAA
SCHEMBL16437744 0.77 KDM4E (0.39) ALDH1A1CYP1A2KDM4EGAAMEN1
SCHEMBL10330347 0.77 ALDH1A1 (0.36) ALDH1A1KDM4EGAAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11713371-B2 Polar functional group-partially introduced polymer, preparation method therefor, and organic electronic element containing same KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2023-08-01 US disclosed
US-11713371-B2 Polar functional group-partially introduced polymer, preparation method therefor, and organic electronic element containing same KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2023-08-01 US disclosed
US-20200308342-A1 POLAR FUNCTIONAL GROUP-PARTIALLY INTRODUCED POLYMER, PREPARATION METHOD THEREFOR, AND ORGANIC ELECTRONIC ELEMENT CONTAINING SAME KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2020-10-01 US disclosed