Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | TET2 | Q6N021 | 3/20 | 0.38 |
| ▸ | TET3 | O43151 | 1/20 | 0.38 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7067240 | 0.82 | ALDH1A1 (0.44) | ALDH1A1TSHRCYP2D6CYP2C19CASP1 | |
| SCHEMBL10457630 | 0.82 | ALDH1A1 (0.44) | ALDH1A1TSHRCYP2D6CYP2C19CASP1 | |
| SCHEMBL179918 | 0.79 | ALDH1A1 (0.45) | ALDH1A1TSHRCYP2D6CYP2C19CASP1 | |
| SCHEMBL19266457 | 0.79 | ALDH1A1 (0.42) | ALDH1A1TSHRCYP2D6CYP2C19CASP1 | |
| SCHEMBL4543582 | 0.78 | ALDH1A1 (0.41) | ALDH1A1TSHRCYP2D6CYP2C19CASP1 | |
| SCHEMBL1604823 | 0.78 | ALDH1A1 (0.41) | ALDH1A1TSHRCYP2D6CYP2C19CASP1 | |
| SCHEMBL22490384 | 0.78 | ALDH1A1 (0.41) | ALDH1A1TSHRCYP2D6CYP2C19CASP1 | |
| SCHEMBL5885445 | 0.78 | ALDH1A1 (0.41) | ALDH1A1TSHRCYP2D6CYP2C19CASP1 | |
| SCHEMBL9747118 | 0.78 | ALDH1A1 (0.44) | ALDH1A1TSHRCYP2D6CYP2C19CASP1 | |
| SCHEMBL11159306 | 0.78 | SOAT1 (0.39) | ALDH1A1TSHRCYP2D6CYP2C19CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3716956-B1 | ANTITUMOR TET2 MODULATING COMPOUNDS | CLEVELAND CLINIC FOUND (US) | 2024-06-26 | — | — | EP | disclosed |
| US-20200306221-A1 | ANTITUMOR TET2 MODULATING COMPOUNDS | THE CLEVELAND CLINIC FOUNDATION | 2020-10-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200306221-A1 | ANTITUMOR TET2 MODULATING COMPOUNDS | TET2, TET1, TET3 | ALDH1A1 1517/4885TSHR 4525/4885CYP2D6 3714/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.