Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | ACACB | O00763 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.43 |
| ▸ | NTRK3 | Q16288 | 2/20 | 0.43 |
| ▸ | NTRK2 | Q16620 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22493047 | 0.91 | EPHX2 (0.51) | KMT2AMAPTMEN1HRH3RAB9A | |
| SCHEMBL19703169 | 0.88 | ALDH1A1 (0.50) | KMT2AMAPTMEN1RAB9ASMN1; SMN2 | |
| SCHEMBL19702699 | 0.88 | ALDH1A1 (0.50) | KMT2AMAPTMEN1RAB9ASMN1; SMN2 | |
| SCHEMBL19702752 | 0.87 | GAA (0.53) | KMT2AMAPTMEN1RAB9ASMN1; SMN2 | |
| SCHEMBL19702684 | 0.87 | ALDH1A1 (0.51) | KMT2AMAPTMEN1RAB9ASMN1; SMN2 | |
| SCHEMBL19702681 | 0.87 | GAA (0.53) | KMT2AMAPTMEN1RAB9ASMN1; SMN2 | |
| SCHEMBL19702686 | 0.86 | KMT2A (0.44) | KMT2AMAPTMEN1RAB9ASMN1; SMN2 | |
| SCHEMBL19702655 | 0.85 | ALDH1A1 (0.49) | KMT2AMAPTMEN1HRH3RAB9A | |
| SCHEMBL19702645 | 0.85 | ALDH1A1 (0.49) | KMT2AMAPTMEN1HRH3RAB9A | |
| SCHEMBL19702692 | 0.85 | ALDH1A1 (0.49) | KMT2AMAPTMEN1HRH3RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200306248-A1 | FORMULATIONS FOR SUBSTITUTED 3-PYRROLIDINES, COMPOSITIONS CONTAINING, AND USES OF, SAME | GDD THERAPEUTICS, LLC (US) | 2020-10-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200306248-A1 | FORMULATIONS FOR SUBSTITUTED 3-PYRROLIDINES, COMPOSITIONS CONTAINING, AND USES OF, SAME | SLC7A1, ABCG2, SLC46A1 | KMT2A 4536/4885MAPT 2779/4885MEN1 3103/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.