Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.52 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.52 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.52 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.52 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.51 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.50 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.50 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.46 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23488173 | 0.89 | CHRNB2 (0.53) | CHRNB2CHRNA5CHRNA7CHRNA4PARP10 | |
| SCHEMBL23488604 | 0.89 | CHRNB2 (0.53) | CHRNB2CHRNA5CHRNA7CHRNA4PARP10 | |
| SCHEMBL22490932 | 0.88 | CHRNB2 (0.50) | CHRNB2CHRNA5CHRNA7CHRNA4PARP10 | |
| SCHEMBL22490872 | 0.88 | CHRNB2 (0.50) | CHRNB2CHRNA5CHRNA7CHRNA4PARP10 | |
| SCHEMBL22490912 | 0.88 | CHRNB2 (0.50) | CHRNB2CHRNA5CHRNA7CHRNA4PARP10 | |
| SCHEMBL23488128 | 0.87 | CHRNB2 (0.51) | CHRNB2CHRNA5CHRNA7CHRNA4PARP10 | |
| SCHEMBL23488668 | 0.87 | CHRNB2 (0.51) | CHRNB2CHRNA5CHRNA7CHRNA4PARP10 | |
| SCHEMBL23488262 | 0.87 | CHRNB2 (0.51) | CHRNB2CHRNA5CHRNA7CHRNA4PARP10 | |
| SCHEMBL22490879 | 0.86 | CHRNB2 (0.48) | CHRNB2CHRNA5CHRNA7CHRNA4PARP10 | |
| SCHEMBL21112887 | 0.85 | SMN1; SMN2 (0.50) | PARP10MAOBSRD5A2TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210170033-A1 | NOVEL CONJUGATES OF A PHARMACEUTICAL AGENT AND A MOIETY CAPABLE OF BINDING TO A GLUCOSE SENSING PROTEIN | SANOFI (FR) | 2021-06-10 | — | — | US | disclosed |
| EP-3717463-A1 | NOVEL CONJUGATES OF A PHARMACEUTICAL AGENT AND A MOIETY CAPABLE OF BINDING TO A GLUCOSE SENSING PROTEIN | Sanofi (FR) | 2020-10-07 | — | — | EP | disclosed |
| CN-111433193-A | Novel conjugates of agents and moieties capable of binding to glucose sensing proteins | 赛诺菲 | 2020-07-17 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210170033-A1 | NOVEL CONJUGATES OF A PHARMACEUTICAL AGENT AND A MOIETY CAPABLE OF BINDING TO A GLUCOSE SENSING PROTEIN | GPR119, SLC2A8, SLC2A4 | CHRNB2 3085/4885CHRNA5 3785/4885CHRNA7 4025/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.