Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 7/20 | 0.43 |
| ▸ | ACE2 | Q9BYF1 | 5/20 | 0.43 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.34 |
| ▸ | MME | P08473 | 3/20 | 0.34 |
| ▸ | CPA1 | P15085 | 1/20 | 0.34 |
| ▸ | FNTA | P49354 | 1/20 | 0.34 |
| ▸ | FNTB | P49356 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5869631 | 0.82 | ACE2 (0.61) | ACEACE2MME | |
| SCHEMBL8254628 | 0.82 | ACE2 (0.61) | ACEACE2MME | |
| SCHEMBL5869812 | 0.80 | ACE (0.58) | ACEACE2MMEFNTAFNTB | |
| SCHEMBL8249070 | 0.80 | ACE (0.58) | ACEACE2MMEFNTAFNTB | |
| SCHEMBL13046895 | 0.79 | ACE2 (0.41) | ACEACE2CPB2CAPN1FNTA | |
| SCHEMBL4686868 | 0.78 | ITGB3 (0.43) | ACEACE2 | |
| SCHEMBL20839555 | 0.78 | ACE2 (0.40) | ACEACE2CAPN1FNTAFNTB | |
| SCHEMBL22491314 | 0.78 | ACE2 (0.38) | ACEACE2CPB2CAPN1FNTA | |
| SCHEMBL8824843 | 0.77 | KDM4E (0.41) | ACEACE2CAPN1FNTAFNTB | |
| SCHEMBL8824831 | 0.77 | KDM4E (0.41) | ACEACE2CAPN1FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3717077-A1 | METHODS FOR MODULATING PIGMENTATION BY ANGIOTENSIN-CONVERTING ENZYME 2 MODULATION | Max-Delbrück-Centrum für Molekulare Medizin in der Helmholtz-Gemeinschaft (DE) | 2020-10-07 | — | — | EP | disclosed |