Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE2 | Q9BYF1 | 4/20 | 0.35 |
| ▸ | ACE | P12821 | 3/20 | 0.35 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.33 |
| ▸ | CPB2 | Q96IY4 | 3/20 | 0.32 |
| ▸ | CPB1 | P15086 | 1/20 | 0.32 |
| ▸ | FNTA | P49354 | 2/20 | 0.31 |
| ▸ | FNTB | P49356 | 2/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.30 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.30 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13046895 | 0.77 | ACE2 (0.41) | ACE2ACECAPN1CPB2CPB1 | |
| SCHEMBL22491299 | 0.77 | ACE2 (0.45) | ACE2ACEFNTAFNTB | |
| SCHEMBL22491307 | 0.77 | ACE2 (0.45) | ACE2ACEFNTAFNTB | |
| SCHEMBL3007905 | 0.77 | ACE (0.49) | ACEMAPK1 | |
| SCHEMBL3007900 | 0.77 | ACE (0.49) | ACEMAPK1 | |
| SCHEMBL7052233 | 0.77 | ACE (0.49) | ACEMAPK1 | |
| SCHEMBL20839555 | 0.76 | ACE2 (0.40) | ACE2ACECAPN1FNTAFNTB | |
| SCHEMBL634586 | 0.76 | ITGA4 (0.45) | ACE2ACECAPN1FNTAFNTB | |
| SCHEMBL22491316 | 0.75 | ACE (0.43) | ACE2ACECAPN1CPB2FNTA | |
| SCHEMBL8824843 | 0.75 | KDM4E (0.41) | ACE2ACECAPN1FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3717077-A1 | METHODS FOR MODULATING PIGMENTATION BY ANGIOTENSIN-CONVERTING ENZYME 2 MODULATION | Max-Delbrück-Centrum für Molekulare Medizin in der Helmholtz-Gemeinschaft (DE) | 2020-10-07 | — | — | EP | disclosed |