SCHEMBL22492074

SCHEMBL22492074

COC(=O)[C@H]1CCC(=O)C[C@@H]1c1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
SLC6A3 Q01959 9/20 0.53
SLC6A4 P31645 7/20 0.53
SLC6A2 P23975 6/20 0.53
ATM Q13315 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15196794 1.00 SLC6A3 (0.53) SLC6A3SLC6A4SLC6A2ATM
SCHEMBL22492077 1.00 SLC6A3 (0.53) SLC6A3SLC6A4SLC6A2ATM
SCHEMBL21611429 0.88 SLC6A3 (0.57) SLC6A3SLC6A4SLC6A2ATM
SCHEMBL21611427 0.88 SLC6A3 (0.57) SLC6A3SLC6A4SLC6A2ATM
SCHEMBL21611425 0.88 SLC6A3 (0.57) SLC6A3SLC6A4SLC6A2ATM
SCHEMBL7668951 0.86 SLC6A3 (0.54) SLC6A3SLC6A4SLC6A2ATM
SCHEMBL16365793 0.86 SLC6A4 (0.47) SLC6A3SLC6A4SLC6A2
SCHEMBL3112421 0.86 SLC6A4 (0.47) SLC6A3SLC6A4SLC6A2
SCHEMBL12151967 0.86 SLC6A4 (0.47) SLC6A3SLC6A4SLC6A2
SCHEMBL3112433 0.86 SLC6A4 (0.47) SLC6A3SLC6A4SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11332472-B2 Substituted piperidines as inhibitors of ubiquitin specific protease 7 LES LABORATOIRES SERVIER (FR) 2022-05-17 US disclosed
US-20200407363-A1 NEW PIPERIDINYL DERIVATIVES AS INHIBITORS OF UBIQUITIN SPECIFIC PROTEASE 7 LES LABORATOIRES SERVIER (FR) 2020-12-31 US disclosed
EP-3717482-A1 NEW PIPERIDINYL DERIVATIVES AS INHIBITORS OF UBIQUITIN SPECIFIC PROTEASE 7 Les Laboratoires Servier SAS (FR) 2020-10-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11332472-B2 Substituted piperidines as inhibitors of ubiquitin specific protease 7 USP7, PSMA7, PSMB7 SLC6A3 4189/4885SLC6A4 4373/4885SLC6A2 4768/4885
US-20200407363-A1 NEW PIPERIDINYL DERIVATIVES AS INHIBITORS OF UBIQUITIN SPECIFIC PROTEASE 7 PSMB7, PSMA7, USP7 SLC6A3 4643/4885SLC6A4 4708/4885SLC6A2 4853/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.