Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14154669 | 1.00 | LMNA (0.52) | LMNAALDH1A1TSHRHSD17B10MEN1 | |
| SCHEMBL29343949 | 1.00 | LMNA (0.52) | LMNAALDH1A1TSHRHSD17B10MEN1 | |
| SCHEMBL22492950 | 1.00 | LMNA (0.52) | LMNAALDH1A1TSHRHSD17B10MEN1 | |
| SCHEMBL6304695 | 1.00 | LMNA (0.52) | LMNAALDH1A1TSHRHSD17B10MEN1 | |
| SCHEMBL22492955 | 1.00 | LMNA (0.52) | LMNAALDH1A1TSHRHSD17B10MEN1 | |
| SCHEMBL20638675 | 1.00 | LMNA (0.52) | LMNAALDH1A1TSHRHSD17B10MEN1 | |
| SCHEMBL27395629 | 0.90 | LMNA (0.48) | LMNAALDH1A1TSHRHSD17B10MEN1 | |
| SCHEMBL27395623 | 0.90 | LMNA (0.48) | LMNAALDH1A1TSHRHSD17B10MEN1 | |
| SCHEMBL27395631 | 0.90 | LMNA (0.48) | LMNAALDH1A1TSHRHSD17B10MEN1 | |
| SCHEMBL22492945 | 0.90 | LMNA (0.60) | LMNAALDH1A1TSHRHSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118388536-A | Novel nucleoside reverse transcriptase inhibitors for antiviral use | 深圳市塔吉瑞生物医药有限公司 | 2024-07-26 | — | — | CN | disclosed |
| CN-109320553-B | Nucleoside reverse transcriptase inhibitors for antiviral use | 深圳市塔吉瑞生物医药有限公司 | 2024-05-14 | — | — | CN | disclosed |
| US-11389463-B2 | Antiviral nucleoside reverse transcriptase inhibitor | SHENZHEN TARGETRX, INC. (CN) | 2022-07-19 | — | — | US | disclosed |
| US-20210093650-A1 | NOVEL ANTIVIRAL NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITOR | SHENZHEN TARGETRX, INC. (CN) | 2021-04-01 | — | — | US | disclosed |
| EP-3719027-A1 | NOVEL ANTIVIRAL NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITOR | Shenzhen TargetRx, Inc. (CN) | 2020-10-07 | — | — | EP | disclosed |
| CN-109320553-A | Novel nucleoside reverse transcriptase inhibitors for antiviral use | 深圳市塔吉瑞生物医药有限公司 | 2019-02-12 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210093650-A1 | NOVEL ANTIVIRAL NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITOR | HPRT1, NUDT1, TYMP | LMNA 3204/4885ALDH1A1 1440/4885TSHR 3448/4885 |
| US-11389463-B2 | Antiviral nucleoside reverse transcriptase inhibitor | HPRT1, TYMP, NUDT1 | LMNA 3201/4885ALDH1A1 1188/4885TSHR 3107/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.