Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.37 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14614806 | 0.78 | CYP1A2 (0.49) | TSHRHSD17B10CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL14436539 | 0.78 | CYP1A2 (0.45) | TSHRHSD17B10CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL23344783 | 0.77 | CYP1A2 (0.48) | TSHRHSD17B10CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL22493241 | 0.76 | BRS3 (0.34) | — | |
| SCHEMBL22400199 | 0.76 | CYP1A2 (0.53) | TSHRHSD17B10CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL22493402 | 0.74 | P2RX7 (0.37) | CYP2C9P2RX7 | |
| SCHEMBL4305773 | 0.74 | CYP1A2 (0.55) | TSHRHSD17B10CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL11859845 | 0.73 | CYP1A2 (0.41) | TSHRHSD17B10CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL18291849 | 0.72 | CYP1A2 (0.49) | TSHRHSD17B10CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL30912118 | 0.72 | CYP1A2 (0.49) | TSHRHSD17B10CYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020198466-A9 | BETA ADRENERGIC AGONIST AND METHODS OF USING THE SAME | CURASEN THERAPEUTICS, INC. (US) | 2020-12-30 | — | — | WO | disclosed |
| WO-2020198466-A1 | BETA ADRENERGIC AGONIST AND METHODS OF USING THE SAME | CURASEN THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |