Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22493858 | 0.82 | TSHR (0.35) | THRBTSHRALDH1A1 | |
| SCHEMBL16985047 | 0.81 | TSHR (0.41) | THRBTSHRALDH1A1 | |
| SCHEMBL23031324 | 0.80 | THRB (0.40) | THRBTSHRALDH1A1 | |
| SCHEMBL975026 | 0.80 | TSHR (0.37) | THRBTSHRALDH1A1 | |
| Hydrochloric Acid SCHEMBL11143194 | 0.78 | THRB (0.36) | THRBTSHRALDH1A1 | |
| SCHEMBL26832159 | 0.78 | THRB (0.43) | THRBTSHRALDH1A1 | |
| SCHEMBL2195083 | 0.78 | THRB (0.52) | THRBTSHRALDH1A1 | |
| SCHEMBL23031113 | 0.76 | THRB (0.41) | THRBTSHRALDH1A1 | |
| SCHEMBL22493851 | 0.75 | TSHR (0.37) | THRBTSHR | |
| SCHEMBL19963575 | 0.74 | THRB (0.42) | THRBTSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4501303-A2 | INORGANIC DENTAL FILLERS INCLUDING A SILANE TREATED SURFACE | Solventum Intellectual Properties Company (US) | 2025-02-05 | — | — | EP | disclosed |
| CN-111565700-B | Inorganic dental filler comprising silane treated surfaces | 3M创新有限公司 | 2023-06-09 | — | — | CN | disclosed |
| EP-3727276-A2 | INORGANIC DENTAL FILLERS INCLUDING A SILANE TREATED SURFACE | 3M Innovative Properties Company (US) | 2020-10-28 | — | — | EP | disclosed |
| US-20200315924-A1 | INORGANIC DENTAL FILLERS INCLUDING A SILANE TREATED SURFACE | SOLVENTUM INTELLECTUAL PROPERTIES COMPANY | 2020-10-08 | — | — | US | disclosed |
| US-20200315924-A1 | INORGANIC DENTAL FILLERS INCLUDING A SILANE TREATED SURFACE | SOLVENTUM INTELLECTUAL PROPERTIES COMPANY | 2020-10-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200315924-A1 | INORGANIC DENTAL FILLERS INCLUDING A SILANE TREATED SURFACE | MSR1, H1-2, H1-3 | THRB 2072/4885TSHR 238/4885ALDH1A1 2155/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.