SCHEMBL22493901

SCHEMBL22493901

CCCCCC/C=C\CCCCCCCCC(=O)OC[C@@H](O)COP(=O)(O)OCCN

nearest known ligand 0.76

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
P2RY10 O00398 11/20 0.76
GPR174 Q9BXC1 9/20 0.76
GPR34 Q9UPC5 6/20 0.76
LPAR1 Q92633 6/20 0.73
ENPP2 Q13822 2/20 0.73
LPAR4 Q99677 2/20 0.73
LPAR5 Q9H1C0 2/20 0.73
LPAR2 Q9HBW0 2/20 0.73
LPAR3 Q9UBY5 2/20 0.73
CES2 O00748 1/20 0.73
LPAR6 P43657 1/20 0.73
TRPV1 Q8NER1 1/20 0.73

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25354353 1.00 P2RY10 (0.76) P2RY10GPR174GPR34LPAR1ENPP2
SCHEMBL31442523 1.00 P2RY10 (0.76) P2RY10GPR174GPR34LPAR1ENPP2
SCHEMBL274999 1.00 P2RY10 (0.76) P2RY10GPR174GPR34LPAR1ENPP2
SCHEMBL14924218 1.00 P2RY10 (0.76) P2RY10GPR174GPR34LPAR1ENPP2
SCHEMBL31442307 1.00 P2RY10 (0.76) P2RY10GPR174GPR34LPAR1ENPP2
SCHEMBL30913715 0.98 LPAR1 (0.73) P2RY10GPR174GPR34LPAR1ENPP2
SCHEMBL32666125 0.97 P2RY10 (0.71) P2RY10GPR174GPR34LPAR1ENPP2
SCHEMBL275621 0.97 P2RY10 (0.71) P2RY10GPR174GPR34LPAR1ENPP2
SCHEMBL17929051 0.97 P2RY10 (0.71) P2RY10GPR174GPR34LPAR1ENPP2
SCHEMBL275624 0.94 LPAR1 (0.67) P2RY10GPR174GPR34LPAR1ENPP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4637812-A1 HEPATITIS B COMPOSITIONS GlaxoSmithKline Biologicals S.A. (BE) 2025-10-29 EP disclosed
EP-4539876-A2 RECOMBINANT RNA MOLECULES COMPRISING UNTRANSLATED REGIONS OR SEGMENTS ENCODING SPIKE PROTEIN FROM THE OMICRON STRAIN OF SEVERE ACUTE RESPIRATORY CORONAVIRUS-2 GlaxoSmithKline Biologicals S.A. (BE) 2025-04-23 EP disclosed
US-20250099576-A1 Recombinant RNA Molecules Comprising Untranslated Regions or Segments Encoding Spike Protein from the Omicron Strain of Severe Acute Respiratory Coronavirus-2 GLAXOSMITHKLINE BIOLOGICALS SA (BE) 2025-03-27 US disclosed
WO-2024133160-A1 HEPATITIS B COMPOSITIONS GLAXOSMITHKLINE BIOLOGICALS SA (BE) 2024-06-27 WO disclosed
US-20240189417-A1 SUBSTITUTION OF NUCLEOTIDE BASES IN SELF-AMPLIFYING MESSENGER RIBONUCLEIC ACIDS GLAXOSMITHKLINE BIOLOGICALS SA (BE) 2024-06-13 US disclosed
WO-2023242817-A2 RECOMBINANT RNA MOLECULES COMPRISING UNTRANSLATED REGIONS OR SEGMENTS ENCODING SPIKE PROTEIN FROM THE OMICRON STRAIN OF SEVERE ACUTE RESPIRATORY CORONAVIRUS-2 GLAXOSMITHKLINE BIOLOGICALS SA (BE) 2023-12-21 WO disclosed
US-20230305011-A1 LIPIDOMICS-BASED IDENTIFICATION OF PATIENTS FOR TREATMENT OF CANCER USING COMPUTED NORMALIZED RATIOS OF CIRCULATING PHOSPHOLIPIDS THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2023-09-28 US disclosed
US-11703508-B2 Lipidomics-based identification of patients bearing ovarian tumors THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2023-07-18 US disclosed
WO-2023031855-A1 SUBSTITUTION OF NUCLEOTIDE BASES IN SELF-AMPLIFYING MESSENGER RIBONUCLEIC ACIDS GLAXOSMITHKLINE BIOLOGICALS SA (BE) 2023-03-09 WO disclosed
US-20200319190-A1 LIPIDOMICS-BASED IDENTIFICATION OF PATIENTS FOR TREATMENT OF CANCER USING COMPUTED NORMALIZED RATIOS OF CIRCULATING PHOSPHOLIPIDS THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2020-10-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250099576-A1 Recombinant RNA Molecules Comprising Untranslated Regions or Segments Encoding Spike Protein from the Omicron Strain of Severe Acute Respiratory Coronavirus-2 RNGTT, RBM25, TMPRSS2 P2RY10 3576/4885GPR174 2621/4885GPR34 3580/4885
US-20240189417-A1 SUBSTITUTION OF NUCLEOTIDE BASES IN SELF-AMPLIFYING MESSENGER RIBONUCLEIC ACIDS NSUN2, NSUN3, RNMT P2RY10 2143/4885GPR174 3092/4885GPR34 3684/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.