Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | GLA | P06280 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.46 |
| ▸ | FYN | P06241 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | AHR | P35869 | 1/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1275568 | 0.86 | KMT2A (0.68) | TDP1KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL29521196 | 0.86 | KMT2A (0.68) | TDP1KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL9334268 | 0.81 | KMT2A (0.80) | TDP1KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL975512 | 0.80 | CYP1A2 (0.53) | TDP1KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL28055564 | 0.79 | TDP1 (0.56) | TDP1KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL14873480 | 0.79 | KDM4E (0.51) | TDP1KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL498807 | 0.79 | KMT2A (0.71) | TDP1KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL975510 | 0.78 | CYP1A2 (0.52) | TDP1KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL13713632 | 0.78 | AKR1B1 (0.58) | TDP1KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL27705873 | 0.78 | CYP1A2 (0.52) | TDP1KMT2AMEN1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3727435-B1 | BIVALENT NUCLEIC ACID LIGANDS AND USES THEREFOR | UNIV CARNEGIE MELLON (US) | 2026-02-18 | — | — | EP | disclosed |
| CN-111757935-B | Bivalent nucleic acid ligands and uses thereof | 卡耐基梅隆大学 | 2025-02-21 | — | — | CN | disclosed |
| US-11859242-B2 | Template-directed nucleic acid targeting compounds | CARNEGIE MELLON UNIVERSITY (US) | 2024-01-02 | — | — | US | disclosed |
| US-20200340044-A1 | Template-Directed Nucleic Acid Targeting Compounds | CARNEGIE MELLON UNIVERSITY | 2020-10-29 | — | — | US | disclosed |
| EP-3728206-A1 | TEMPLATE-DIRECTED NUCLEIC ACID TARGETING COMPOUNDS | CARNEGIE MELLON UNIVERSITY (US) | 2020-10-28 | — | — | EP | disclosed |
| EP-3727435-A1 | BIVALENT NUCLEIC ACID LIGANDS AND USES THEREFOR | CARNEGIE MELLON UNIVERSITY (US) | 2020-10-28 | — | — | EP | disclosed |
| CN-111801317-A | Template-directed nucleic acid-targeting compounds | 卡耐基梅隆大学 | 2020-10-20 | — | — | CN | disclosed |
| CN-111757935-A | Bivalent nucleic acid ligand and use thereof | 卡耐基梅隆大学 | 2020-10-09 | — | — | CN | disclosed |
| US-20200318195-A1 | Bivalent Nucleic Acid Ligands and Uses Therefor | CARNEGIE MELLON UNIVERSITY | 2020-10-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200340044-A1 | Template-Directed Nucleic Acid Targeting Compounds | TARDBP, HTT, TRDMT1 | TDP1 64/4885KMT2A 846/4885MEN1 1494/4885 |
| US-11859242-B2 | Template-directed nucleic acid targeting compounds | TARDBP, HTT, TRDMT1 | TDP1 64/4885KMT2A 846/4885MEN1 1494/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.