Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5593603 | 0.81 | KMT2A (0.54) | KMT2AMEN1KDM4ETDP1CYP1A2 | |
| SCHEMBL22493918 | 0.78 | TDP1 (0.56) | AKR1B1KMT2AMEN1KDM4ETDP1 | |
| SCHEMBL1003594 | 0.78 | CYP1A2 (0.68) | KMT2AMEN1KDM4ETDP1CYP1A2 | |
| SCHEMBL6390932 | 0.78 | KMT2A (0.46) | AKR1B1KMT2AMEN1KDM4ETDP1 | |
| 2-Naphthylacetic Acid SCHEMBL29366514 | 0.78 | NR1H4 (0.71) | AKR1B1KMT2AMEN1KDM4ETDP1 | |
| 2-Naphthylacetic Acid SCHEMBL238445 | 0.78 | NR1H4 (0.71) | AKR1B1KMT2AMEN1KDM4ETDP1 | |
| 2-Naphthylacetic Acid SCHEMBL30493868 | 0.78 | NR1H4 (0.71) | AKR1B1KMT2AMEN1KDM4ETDP1 | |
| 2-Naphthylacetic Acid SCHEMBL28641469 | 0.78 | NR1H4 (0.71) | AKR1B1KMT2AMEN1KDM4ETDP1 | |
| SCHEMBL23070737 | 0.77 | AKR1B1 (0.60) | AKR1B1KMT2AMEN1KDM4ETDP1 | |
| SCHEMBL756841 | 0.76 | PTGS1 (0.71) | AKR1B1KMT2AMEN1KDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3727435-B1 | BIVALENT NUCLEIC ACID LIGANDS AND USES THEREFOR | UNIV CARNEGIE MELLON (US) | 2026-02-18 | — | — | EP | disclosed |
| CN-111757935-B | Bivalent nucleic acid ligands and uses thereof | 卡耐基梅隆大学 | 2025-02-21 | — | — | CN | disclosed |
| US-11859242-B2 | Template-directed nucleic acid targeting compounds | CARNEGIE MELLON UNIVERSITY (US) | 2024-01-02 | — | — | US | disclosed |
| US-20200340044-A1 | Template-Directed Nucleic Acid Targeting Compounds | CARNEGIE MELLON UNIVERSITY | 2020-10-29 | — | — | US | disclosed |
| EP-3727435-A1 | BIVALENT NUCLEIC ACID LIGANDS AND USES THEREFOR | CARNEGIE MELLON UNIVERSITY (US) | 2020-10-28 | — | — | EP | disclosed |
| EP-3728206-A1 | TEMPLATE-DIRECTED NUCLEIC ACID TARGETING COMPOUNDS | CARNEGIE MELLON UNIVERSITY (US) | 2020-10-28 | — | — | EP | disclosed |
| CN-111801317-A | Template-directed nucleic acid-targeting compounds | 卡耐基梅隆大学 | 2020-10-20 | — | — | CN | disclosed |
| CN-111757935-A | Bivalent nucleic acid ligand and use thereof | 卡耐基梅隆大学 | 2020-10-09 | — | — | CN | disclosed |
| US-20200318195-A1 | Bivalent Nucleic Acid Ligands and Uses Therefor | CARNEGIE MELLON UNIVERSITY | 2020-10-08 | — | — | US | disclosed |
| US-20090220381-A1 | IMAGEWISE PATTERNING OF FILMS AND DEVICES COMPRISING THE SAME | NESTEC S.A. (CH) | 2009-09-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200340044-A1 | Template-Directed Nucleic Acid Targeting Compounds | TARDBP, HTT, TRDMT1 | AKR1B1 2466/4885KMT2A 846/4885MEN1 1494/4885 |
| US-11859242-B2 | Template-directed nucleic acid targeting compounds | TARDBP, HTT, TRDMT1 | AKR1B1 2466/4885KMT2A 846/4885MEN1 1494/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.