Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 6/20 | 0.61 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.48 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.45 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.45 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 2/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22525292 | 0.98 | ACE (0.59) | ACEMTNR1BSOAT2SOAT1FAAH | |
| SCHEMBL3609218 | 0.93 | ACE (0.70) | ACEMTNR1B | |
| SCHEMBL22494107 | 0.89 | ACE (0.60) | ACESOAT2SOAT1TBXA2RFAAH | |
| SCHEMBL22494121 | 0.89 | ACE (0.60) | ACESOAT2SOAT1TBXA2RFAAH | |
| SCHEMBL22494104 | 0.89 | ACE (0.60) | ACESOAT2SOAT1TBXA2RFAAH | |
| SCHEMBL22525274 | 0.87 | ACE (0.58) | ACESOAT2SOAT1TBXA2RFAAH | |
| SCHEMBL22494114 | 0.87 | ACE (0.58) | ACESOAT2SOAT1TBXA2RFAAH | |
| SCHEMBL22494116 | 0.87 | ACE (0.58) | ACESOAT2SOAT1TBXA2RFAAH | |
| SCHEMBL9221105 | 0.82 | ACE (0.68) | ACEMTNR1B | |
| SCHEMBL3612165 | 0.79 | ACE (0.50) | ACEMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11365177-B2 | Chemical uncouplers of respiration and methods of use thereof | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2022-06-21 | — | — | US | disclosed |
| US-11365177-B2 | Chemical uncouplers of respiration and methods of use thereof | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2022-06-21 | — | — | US | disclosed |
| US-20200317613-A1 | CHEMICAL UNCOUPLERS OF RESPIRATION AND METHODS OF USE THEREOF | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED | 2020-10-08 | — | — | US | disclosed |
| US-20200317613-A1 | CHEMICAL UNCOUPLERS OF RESPIRATION AND METHODS OF USE THEREOF | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED | 2020-10-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11365177-B2 | Chemical uncouplers of respiration and methods of use thereof | PC, UQCRC1, SQOR | ACE 1610/4885MTNR1B 484/4885SOAT2 1133/4885 |
| US-20200317613-A1 | CHEMICAL UNCOUPLERS OF RESPIRATION AND METHODS OF USE THEREOF | PC, UQCRC1, SQOR | ACE 1610/4885MTNR1B 484/4885SOAT2 1133/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.