Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 2/20 | 0.41 |
| ▸ | RICTOR | Q6R327 | 2/20 | 0.41 |
| ▸ | RPTOR | Q8N122 | 2/20 | 0.41 |
| ▸ | MAPKAP1 | Q9BPZ7 | 2/20 | 0.41 |
| ▸ | MLST8 | Q9BVC4 | 2/20 | 0.41 |
| ▸ | CDK1 | P06493 | 2/20 | 0.36 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.36 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.36 |
| ▸ | CDK2 | P24941 | 2/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 3/20 | 0.32 |
| ▸ | PI4KA | P42356 | 1/20 | 0.32 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.32 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.32 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.32 |
| ▸ | DHFR | P00374 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29399563 | 0.82 | CDK1 (0.44) | MTORRICTORRPTORMAPKAP1MLST8 | |
| SCHEMBL21459294 | 0.82 | CDK1 (0.44) | MTORRICTORRPTORMAPKAP1MLST8 | |
| SCHEMBL130702 | 0.70 | PI4KA (0.56) | CDK1CCNB1CCNE1CDK2PI4KA | |
| SCHEMBL253674 | 0.69 | ADORA2A (0.32) | SLC2A1DHFR | |
| SCHEMBL22494329 | 0.69 | MTOR (0.50) | MTORRICTORRPTORMAPKAP1MLST8 | |
| SCHEMBL22494331 | 0.69 | MTOR (0.50) | MTORRICTORRPTORMAPKAP1MLST8 | |
| SCHEMBL30381902 | 0.69 | MTOR (0.50) | MTORRICTORRPTORMAPKAP1MLST8 | |
| SCHEMBL24500614 | 0.68 | KDM4E (0.42) | PI4KAPI4K2BPI4K2API4KBKDM4E | |
| Hydrochloric Acid SCHEMBL29448490 | 0.68 | XDH (0.43) | CDK1CCNB1CCNE1CDK2 | |
| SCHEMBL31403538 | 0.67 | KDM4E (0.41) | MTORRICTORRPTORMAPKAP1MLST8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4370517-A1 | SYNTHESIS OF CHIRAL SUBSTITUTED PYRAZOLOPYRIMIDINE COMPOUNDS | Galderma Holding SA (CH) | 2024-05-22 | — | — | EP | disclosed |
| WO-2023285926-A1 | SYNTHESIS OF CHIRAL SUBSTITUTED PYRAZOLOPYRIMIDINE COMPOUNDS | Galderma Holding SA (CH) | 2023-01-19 | — | — | WO | disclosed |