⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1314535 | 0.84 | ALDH1A1 (0.33) | — | |
| SCHEMBL2108706 | 0.73 | — | — | |
| SCHEMBL204460 | 0.73 | — | — | |
| SCHEMBL621375 | 0.71 | — | — | |
| SCHEMBL203426 | 0.71 | — | — | |
| SCHEMBL124324 | 0.69 | — | — | |
| SCHEMBL2021034 | 0.67 | — | — | |
| SCHEMBL549136 | 0.67 | TSHR (0.38) | — | |
| SCHEMBL445463 | 0.67 | — | — | |
| SCHEMBL12677819 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12060373-B2 | Chalcogenosilacyclopentanes | GELEST, INC. (US) | 2024-08-13 | — | — | US | disclosed |
| US-20230098287-A1 | CHALCOGENOSILACYCLOPENTANES | GELEST TECHNOLOGIES, INC. | 2023-03-30 | — | — | US | disclosed |
| US-11542284-B2 | Chalcogenosilacyclopentanes | GELEST, INC. (US) | 2023-01-03 | — | — | US | disclosed |
| EP-3947400-A1 | CHALCOGENOSILACYCLOPENTANES | GELEST, INC. (US) | 2022-02-09 | — | — | EP | disclosed |
| CN-113710677-A | Oxosilane cyclopentane | 盖列斯特有限公司 | 2021-11-26 | — | — | CN | disclosed |
| US-20200317699-A1 | Chalcogenosilacyclopentanes | GELEST, INC. | 2020-10-08 | — | — | US | disclosed |
| WO-2020205298-A1 | CHALCOGENOSILACYCLOPENTANES | GELEST TECHNOLOGIES, INC. (US) | 2020-10-08 | — | — | WO | disclosed |