SCHEMBL549136

SCHEMBL549136

CC(C)C[Si](Cl)(CC(C)C)CC(C)C

nearest known ligand 0.38

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL445463 0.77
SCHEMBL2021034 0.77
SCHEMBL621375 0.74
SCHEMBL1314535 0.74 ALDH1A1 (0.33)
SCHEMBL203426 0.74
SCHEMBL2160168 0.72
SCHEMBL5028326 0.72
SCHEMBL5027516 0.69
SCHEMBL7765406 0.69
SCHEMBL11650603 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 261 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4028379-B1 IMPROVED METHOD FOR THE PREPARATION OF CYCLOPROYL COMPOUNDS FROM ALKENES SALTIGO GMBH (DE) 2025-11-19 EP claimed
CN-120025537-A Atomic oxygen-resistant polyether-ether-ketone material for aviation, preparation method thereof and composite material 南京工业大学 2025-05-23 CN claimed
US-20250060673-A1 DEVELOPMENT STRATEGY FOR HIGH-ABSORBING METAL-CONTAINING PHOTORESISTS LAM RES CORP (US) 2025-02-20 US claimed
CN-119059879-A Cyclopropanation of substituted olefins 国际香料和香精公司 2024-12-03 CN claimed
CN-117982404-A Ocular surface slow release drug delivery implant capable of adjusting drug release rate and preparation method thereof 复旦大学附属眼耳鼻喉科医院 2024-05-07 CN claimed
WO-2023115023-A1 DEVELOPMENT STRATEGY FOR HIGH-ABSORBING METAL-CONTAINING PHOTORESISTS LAM RESEARCH CORPORATION (US) 2023-06-22 WO claimed
US-11670512-B2 Selective deposition on silicon containing surfaces VERSUM MATERIALS US, LLC (US) 2023-06-06 US claimed
US-20220348526-A1 Improved process for preparing cyclopropyl compounds from alkenes SALTIGO GMBH (DE) 2022-11-03 US claimed
EP-4028379-A1 IMPROVED PROCESS FOR PREPARING CYCLOPROPYL COMPOUNDS FROM ALKENES Saltigo GmbH (DE) 2022-07-20 EP claimed
CN-114401938-A Improved process for the preparation of cyclopropyl compounds from olefins 赛拓有限责任公司 2022-04-26 CN claimed
EP-3331843-A1 CYCLOPROPANATION OF SUBSTITUTED ALKENES International Flavors & Fragrances Inc. (US) 2018-06-13 EP claimed
CN-107848907-A Cyclopropanation of substituted olefins 国际香料和香精公司 2018-03-27 CN claimed
WO-2017024126-A1 CYCLOPROPANATION OF SUBSTITUTED ALKENES INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 2017-02-09 WO claimed
US-20110009582-A1 Preparation of Activating Supports TOTAL PETROCHEMICALS RESEARCH FELUY (BE) 2011-01-13 US claimed
EP-2170511-A1 PREPARATION OF ACTIVATING SUPPORTS Total Petrochemicals Research Feluy (BE) 2010-04-07 EP claimed
WO-2009013197-A1 PREPARATION OF ACTIVATING SUPPORTS TOTAL PETROCHEMICALS RESEARCH FELUY (BE) 2009-01-29 WO claimed
US-6365643-B1 Photoinitiators for cationic curing TH. GOLDSCHMIDT AG (DE) 2002-04-02 US claimed
EP-0905130-B1 A process for the production of taxol COUNCIL SCIENT IND RES (IN) 2002-03-06 EP claimed
EP-0905130-A1 A process for the production of taxol Council of Scientific and Industrial Research (IN) 1999-03-31 EP claimed
US-5856532-A ISOLATING THE XYLOSIDE ANALOGUE OF TAXOLS FROM STEM BARK OF TAXUS WALLICHIANA, EXTRACTING, HEATING, PRECIPITATING, DISSOLVING IN A SOLVENT, CLEAVING DIOL OF XYLOSIDE TO DIALDEHYDE, REDUCING, ACETYLATING, PROTECTING, DEPROTECTING COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 1999-01-05 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220348526-A1 Improved process for preparing cyclopropyl compounds from alkenes CYP4F3, CXXC4, ZRANB2 TSHR 3420/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.