Chrysene

Chrysene

SCHEMBL22495970

c1ccc2c(c1)ccc1c3ccccc3ccc21.c1ccc2cc3ccccc3cc2c1

nearest known ligand 0.82

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPRT1 P00492 4/20 0.82
ALDH1A1 P00352 5/20 0.71
HSD17B10 Q99714 4/20 0.71
CYP2A6 P11509 1/20 0.71
TSHR P16473 1/20 0.71
TDP1 Q9NUW8 1/20 0.71
CYP1B1 Q16678 2/20 0.65
HIF1A Q16665 1/20 0.65
PAX8 Q06710 1/20 0.56
CYP1A2 P05177 5/20 0.56
ERBB2 P04626 1/20 0.56
FYN P06241 1/20 0.56
MAOA P21397 1/20 0.56
ACHE P22303 1/20 0.56
AHR P35869 1/20 0.56
HPGD P15428 3/20 0.52
MAPT P10636 2/20 0.50
LMNA P02545 1/20 0.50
CYP3A4 P08684 1/20 0.50
APEX1 P27695 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Chrysene SCHEMBL21954859 0.97 HPRT1 (0.78) HPRT1ALDH1A1HSD17B10CYP2A6TSHR
Phenanthrene SCHEMBL3339627 0.94 ALDH1A1 (0.80) HPRT1ALDH1A1HSD17B10CYP2A6TSHR
SCHEMBL308409 0.92 ALDH1A1 (0.80) HPRT1ALDH1A1HSD17B10CYP2A6TSHR
Chrysene SCHEMBL588025 0.92 ALDH1A1 (0.80) HPRT1ALDH1A1HSD17B10CYP2A6TSHR
SCHEMBL4855008 0.92 ALDH1A1 (0.80) HPRT1ALDH1A1HSD17B10CYP2A6TSHR
SCHEMBL4845538 0.92 ALDH1A1 (0.80) HPRT1ALDH1A1HSD17B10CYP2A6TSHR
SCHEMBL30954352 0.92 ALDH1A1 (0.80) HPRT1ALDH1A1HSD17B10CYP2A6TSHR
SCHEMBL5470723 0.92 ALDH1A1 (0.80) HPRT1ALDH1A1HSD17B10CYP2A6TSHR
SCHEMBL4847360 0.92 ALDH1A1 (0.80) HPRT1ALDH1A1HSD17B10CYP2A6TSHR
Phenanthrene SCHEMBL28211822 0.91 CYP2A6 (0.75) HPRT1ALDH1A1HSD17B10CYP2A6TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200321539-A1 ORGANIC LIGHT-EMITTING COMPOSITE MATERIAL AND AN ORGANIC LIGHT-EMITTING DEVICE COMPRISING THE SAME VALIANT CO., LTD. 2020-10-08 US disclosed