Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 2/20 | 0.50 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 1/20 | 0.48 |
| ▸ | MMP1 | P03956 | 1/20 | 0.48 |
| ▸ | MMP12 | P39900 | 1/20 | 0.48 |
| ▸ | PRKCA | P17252 | 1/20 | 0.48 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.48 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.47 |
| ▸ | TGM2 | P21980 | 1/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6989373 | 0.84 | KCNA5 (0.57) | KCNA5LMNA | |
| SCHEMBL22497529 | 0.82 | GRIK1 (0.59) | NR4A2MMP1MMP12PRKCAPRKCD | |
| SCHEMBL30279458 | 0.82 | GRIK1 (0.59) | NR4A2MMP1MMP12PRKCAPRKCD | |
| SCHEMBL6647004 | 0.75 | PRKCA (0.62) | NR4A2PPARGPPARAMMP1MMP12 | |
| SCHEMBL23864576 | 0.74 | KMT2A (0.66) | LMNAMAPK14 | |
| SCHEMBL2453780 | 0.74 | NR4A2 (0.62) | NR4A2MRGPRX4 | |
| SCHEMBL2207411 | 0.74 | KCNA5 (0.68) | KCNA5LMNA | |
| SCHEMBL22524917 | 0.74 | PRKCA (0.55) | MMP1MMP12PRKCAPRKCDMGLL | |
| SCHEMBL3415287 | 0.73 | PTGDR2 (0.64) | PTGDR2PPARAMGLL | |
| SCHEMBL6430890 | 0.73 | CFD (0.69) | MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020199945-A1 | ORTHO-CARBONYL AMINO-SUBSTITUTED BENZENE DERIVATIVE, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 中国医学科学院药物研究所 | 2020-10-08 | — | — | WO | disclosed |